Results 101 to 110 of about 595,690 (305)
Cooperative Marketing of Animal Health Products [PDF]
This report uses eight case studies to identify elements of successful cooperative programs for retailing over-the-counter animal health products (AHP).
Vogelsang, Donald L.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Lessons from the History of Over-the-Counter Derivatives Regulation [PDF]
, 2011 The approach of Problem-based learning (PBL), which was used for the first time in medical education at Mc Master University, is the main teaching method within the field of European Studies at Maastricht University, both at Master and Bachelor level ...
Maxfield, Sylvia
core
Over-the-counter suboptimal dispensing of antibiotics in Uganda
Journal of Multidisciplinary Healthcare, 2013 Jackson K Mukonzo,1,2 Proscovia M Namuwenge,1 Gildo Okure,3 Benjamin Mwesige,1 Olivia K Namusisi,4 David Mukanga4 1Center for Operational Research Africa, Kampala, Uganda; 2Department of Pharmacology and Therapeutics, 3School of Public Health, Makerere ...
Mukonzo JK +5 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Emergence and Future of Central Counterparties [PDF]
We study the role of a central counterparty (CCP) in controlling counterparty risk. When trading is organized via a centralized exchange with fungible contracts -- as in a futures market -- we show that it is optimal to clear trades via a CCP that uses ...
Cyril Monnet, Thorsten V. Koeppl
core +3 more sources
Over-the-counter weight loss preparations [PDF]
, 2015 Obesity has been described as a pandemic as it is estimated to contribute to more than 3 million deaths worldwide.2 In Malta 28.7% of the population is obese and another 67.6% is classified as overweight.3, 4 This paper will be provide a summary of ...
Vella, Valerie
core
پزشکی بالینی ابن سینا, 2016 Introduction & Objective: Pharmacists usually encounter requests for over the counter drugs. How a pharmacist performs in evaluating patientschr('39') signs and symptoms, treating them, and moreover his or her approach in prescribing over the counter ...
A. Rashidi +3 more
doaj