Results 111 to 120 of about 595,690 (305)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Hand-Held Instrument Fights Acne, Tops Over-the-Counter Market [PDF]

, 2007
Tyrell Inc., a Houston-based medical technologies company, was able to access engineering support in redesigning a heating element for a hand-held acne-fighting device through SATOP, NASA's Space Alliance Technology Outreach Program.

core   +1 more source

A Comparative Study on The Reasons for Use and Non-Use of Self-Medication Among Students of a Medical College in Western Uttar Pradesh

National Journal of Community Medicine, 2016
Background: Self-medication is selection and use of non-prescription medicines by individuals’ own initiatives to treat self-recognized illnesses or symptoms.
Shyam B Gupta , Danish Imtiaz, Ved Prakash Shrotriya, Atul Kumar Singh   +3 more
doaj  

Unveiling pedagogical effects of blended multimedia and slide-based approaches on students’ self-efficacy and performance in over-the-counter medication counseling: an explanatory mixed methods study

BMC Medical Education
Background Addressing healthcare communication skills through a multimedia approach may enrich undergraduate pharmacy students’ medication counseling competence.
Yen-Ming Huang, Fang-Ju Lin, Yao-Hsing Wang, Olayinka Shiyanbola, Hsun-Yu Chan, Yunn-Fang Ho   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Alternative remedies for insomnia: a proposed method for personalized therapeutic trials

Nature and Science of Sleep, 2017
Kate Romero,1,2 Balaji Goparaju,1,2 Kathryn Russo,1,2 M Brandon Westover,1 Matt T Bianchi1,2 1Neurology Department, Massachusetts General Hospital, 2Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA Abstract: Insomnia is a common ...
Romero K, Goparaju B, Russo K, Westover MB, Bianchi MT   +4 more
doaj  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Reforming the over-the-counter derivatives market: what’s to be gained? [PDF]

While derivative financial instruments have made the hedging and exchange of risk more efficient, the recent crisis showed that they also pose a substantial threat to financial stability in times of systemic turmoil. Underlying much of this threat is the
Ben R. Craig, Kent Cherny
core  

Knowledge, Attitude, and Practice on Over-the-Counter Drugs among Medical Students University of Khartoum, 2022-2023

International Journal of Medical Students
Background: Self-medication with over-the-counter (OTC) medications is common among medical students. It is influenced by many factors, such as age, sex, income, self-care orientation, and medical knowledge.
Iyas Abdelhadi Ahmed Abdelhadi
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source