Results 81 to 90 of about 502,761 (308)

Factors associated with the use of dietary supplements and over-the-counter medications in Japanese elderly patients

BMC Family Practice, 2018
Background The use of dietary supplements and over-the-counter (OTC) drugs is increasing, and there is adequate concern about potential harmful effects.
Shoichi Masumoto, Mikiya Sato, Takami Maeno, Yumiko Ichinohe, Tetsuhiro Maeno   +4 more
doaj   +1 more source

DHLP 1&2: Giraph based distributed label propagation algorithms on heterogeneous drug-related networks

, 2020
Background and Objective: Heterogeneous complex networks are large graphs consisting of different types of nodes and edges. The knowledge extraction from these networks is complicated. Moreover, the scale of these networks is steadily increasing.
Ghadiri, Nasser, Maleki, Erfan Farhangi, Maleki, Zeinab, Shahreza, Maryam Lotfi   +3 more
core   +1 more source

Concurrent use of prescription drugs and herbal medicinal products in older adults: A systematic review [PDF]

, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction ...
A Cherubini, A Djuv, A Fugh-Berman, A Gonzalez-Stuart, A Robinson, A Tsang, AA Izzo, AA Izzo, AA Mangoni, AM Loya, Barbara Wider, C Batanero-Hernán, CA Parkman, CC Peng, Claire Goodman, Commission of the European Communities, DH Mehta, DM Qato, DM Qato, DW Kaufman, E Vacas Rodilla, EC Davies, EM Williamson, FP Turkmenoglu, G Nyborg, GW Elmer, J Jerez-Roig, J Kavanagh, J Kennedy, J Ly, J Peklar, J Sultana, JE Souza Silva de, JJ Bruno, JM Dergal, JS Marinac, K Radimer, KA Vickers, L Howell, L Shamseer, L Shane-McWhorter, Leala K. Watson, MA Raji, ME Levine, MHRA, Ipsos MORI, MS Lantz, N Lynch, N Samuels, P Gardiner, P Posadzki, PH Canter, R Delgoda, RL Nahin, S Hilmer, S Singh, S Yoon, SJ Blalock, SJ Yoon, SL Yoon, SR Singh, T Agbabiaka, Taofikat B. Agbabiaka, The Joanna Briggs Institute, W Leiss, X-L Zhang, Z Munn   +65 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Alcohol and other drug treatment and diversion from the Australian criminal justice system: 2012-13 [PDF]

Nationally, there were 24,069 clients who had been diverted into alcohol and other drug treatment, comprising 24% of all clients, according to this report.

core  

Negotiating the Resistance: Catch 22s, brokering and contention in Occupy Safer Spaces Policy [PDF]

, 2015
In the post 2008 financial crisis climate we have seen a plethora of protest movements emerge globally with one of the most recognisable, particularly in the western context, being that of the Occupy movement, which sought to contest the global ...
Fletcher, Samantha
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Nudging the FDA [PDF]

, 2014
[Excerpt] The FDA’s regulation of drugs is frequently the subject of policy debate, with arguments falling into two camps. On the one hand, a libertarian view of patients and the health care system holds high the value of consumer choice.
Cohen, I. Glenn, Price, W. Nicholson, II
core   +1 more source

Release of proteins via ion exchange from albumin-heparin microspheres [PDF]

, 1992
Albumin-heparin and albumin microspheres were prepared as ion exchange gels for the controlled release of positively charged polypeptides and proteins.
Bae, You Han, Cremers, H.F.M., Cremers, Harry, Feijen, Jan, Kim, Sung Wan, Kwon, Glen S.   +5 more
core   +3 more sources