Results 121 to 130 of about 563,471 (308)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Major technical issues with increased PV penetration on the existing electrical grid
, 2012 In the past decade, the installation of rooftop PV (Photovoltaic) systems has substantially increased in many countries. This increase is anticipated due to government incentives like RECs (Renewable Energy Certificates) and feed-in tariff, to ...
Jadeja, Kalpendrasinh
core
Effects of PEV Penetration on Voltage Unbalance
, 2014 Balancing loads in low voltage networks is a challenging task due to a continuous fluctuation in the power demand. Voltage unbalance is a condition in which the voltage phasors differ in amplitude and/or do not have its normal 120° phase relationship ...
Ahmed M. A. Haidar +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Research of over-voltage of coal mine power system
Gong-kuang zidonghua, 2013 In view of problem that 35 kV power system of a Coal Mine often happens over-voltage at thunderstorm day, the paper analyzed causes of over-voltage, indicated that over-voltage was induced by fraction frequency resonance and the fraction frequency ...
XU Jian-ju
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Rating methodology of high voltage mass impregnated DC cable circuits
, 2014 With the continuing growth in energy consumption worldwide, the move towards a European wide super grid will result in significant changes in how modern transmission and distribution networks are operated.
Huang, Ziyi
core