Results 61 to 70 of about 87,203 (259)

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

open access: yesAdvanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu   +16 more
wiley   +1 more source

Overactive bladder: the importance of tailoring treatment to the individual patient

open access: yes, 2011
Harold P DrutzDepartment of Obstetrics and Gynecology, Mount Sinai Hospital, University of Toronto, Ontario, CanadaOn behalf of the Specialist Advisory Group on OAB (Lake Como, Italy, June 2009)Introduction: Overactive bladder (OAB) is a prevalent and ...
Drutz HP, Michelle Thorpe
core   +1 more source

Conservative treatments for overactive bladder [PDF]

open access: yes, 2015
Tüm kılavuzlarda, aşırı aktif mesane hastalığının ilk basamak tedavisinde konservatif yöntemler önerilmektedir. Bu makalede aşırı aktif mesane tedavisinde konservatif tedavilerin yeri ve etkinliği literatür bilgileri ışığında değerlendirilmiştir ...
Dede, Onur   +2 more
core   +3 more sources

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Association between Menopausal Symptoms and Overactive Bladder: A Cross-Sectional Questionnaire Survey in China.

open access: yesPLoS ONE, 2015
PurposeThe association between menopause and overactive bladder is controversial. The purpose of this study was to determine the association between menopausal symptoms and overactive bladder, and identify the risk factors for overactive bladder.MethodsA
Lingping Zhu   +10 more
doaj   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Making Rasch decisions: the use of Rasch analysis in the construction of preference based health related quality of life instruments [PDF]

open access: yes
Objective: To set out the methodological process for using Rasch analysis alongside traditional psychometric methods in the development of a health state classification that is amenable to valuation.
Tsuchiya, A   +4 more
core  

Evaluation of blood pressure in children with idiopathic overactive bladder syndrome

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2018
Children with an overactive bladder generally exhibit frequency, urgency, and urge incontinence. Often, a child will squat to try to prevent urinary incontinence.
Parsa Yousefichaijan   +4 more
doaj   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

open access: yesAdvanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian   +12 more
wiley   +1 more source

Overactive bladder: strategies to ensure treatment compliance and adherence

open access: yes, 2016
Prabhpreet Dhaliwal, Adrian Wagg Department of Medicine, University of Alberta, Edmonton, Canada Abstract: Overactive bladder is a common, debilitating condition for many patients who may benefit from pharmacological management of their condition ...
Dhaliwal P, Wagg A
core  

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