Results 71 to 80 of about 87,203 (259)
Cadherin-11 up-regulation in overactive bladder suburothelial myofibroblasts
, 2009 PURPOSE: We investigated whether the adherens junction proteins cadherin-11 and beta-catenin can be immunohistochemically visualized in the human bladder using commercially available antibodies and, if so, whether there are differences between patients ...
Panicker, Jalesh +16 more
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, 2020 In recent years, there has been a steady increase in patients visiting a specialist for what is known as overactive bladder syndrome. Due to the extremely negative impact of the disease on patients' quality of life, timely diagnosis and adequate ...
Yordanov Delyan, Yordanova Lilyna
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Taiwanese Journal of Obstetrics & Gynecology, 2020 Objectives: Some symptoms of overactive bladder overlap with those of interstitial cystitis. This study was conducted to compare the urodynamic results and quality of life of patients with the two conditions.
Chin-Chieh Hsu +4 more
doaj +1 more source
Advanced Science, EarlyView.A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang +17 more
wiley +1 more source
Advanced Science, EarlyView.This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang +10 more
wiley +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Review of the epidemiology of overactive bladder
, 2016 Renu S Eapen, Sidney B Radomski Division of Urology, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, ON, Canada Abstract: Overactive bladder (OAB) is common in both men and women.
Eapen RS, Radomski SB
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, 2017 To evaluate the changes in dynamic pupillometry in patients with idiopathic overactive bladder (OAB)
Ebiloglu, Turgay +5 more
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Interleukin‐39 is a Prognostic Biomarker and Therapy Target for Sepsis
Advanced Science, EarlyView.Sepsis triggers a significant increase in IL‐39 production, with circulating levels markedly elevated and positively correlated with disease severity and poor clinical prognosis in sepsis patients. Mechanistically, macrophage‐derived IL‐39 activates the GP130 signaling pathway via a ligand‐receptor interaction, thereby fueling the pro‐inflammatory ...
Feng‐zhi Zhang +9 more
wiley +1 more source
Pharmacologic management of overactive bladder
, 2007 Sum Lam1,2, Olga Hilas1,31St. John’s University, College of Pharmacy and Allied Health Professions, Department of Clinical Pharmacy Practice, Queens, New York, USA; 2Division of Geriatric Medicine, Winthrop University Hospital, Mineola, New York ...
Olga Hilas, Sum Lam
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