Results 91 to 100 of about 87,203 (259)
Objective: To investigate the association of bladder wall thickness (BWT) with severity of symptoms in overactive bladder patients in Obstetrics and Gynecology Department Dr. Mohammad Hoesin general hospital Palembang.
Ronny Adrian +3 more
doaj +1 more source
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Choice of antimuscarinic agents for overactive bladder in the older patient: focus on darifenacin
Bilal Chughtai1, Robert Levin2, Elise De11Albany Medical College, Division of Urology; 2Albany College of Pharmacy and Stratton VAMC, Albany, NY, USAAbstract: Overactive bladder (OAB) is a difficult condition to live with and is very costly tothe ...
Bilal Chughtai, Robert Levin, Elise De
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Effect of Bladder Training and Pelvic Floor Muscle Exercises on Urge Control among Patients with Overactive Bladder Syndrome. [PDF]
Background: Overactive bladder (OAB) is a major public health problem affecting millions of men and women worldwide. It is an embarrassing condition with a negative effect on quality of life. So, a combination of pharmacological and behavioral therapy is
Zeinab Abou Shareb +3 more
doaj +1 more source
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee +3 more
wiley +1 more source
Patient perspectives in the management of overactive bladder, focus on transdermal oxybutynin
Tondalaya Gamble, Peter SandEvanston Continence Center, Division of Urogynecology, Department of Obstetrics and Gynecology, Evanston Northwestern Healthcare, Northwestern University, Feinberg School of Medicine, Evanston, IllinoisAbstract: Overactive ...
Tondalaya Gamble, Peter Sand
core
Mirabegron for Overactive Bladder: A Novel, First-in-Class β3- Agonist Therapy
Purpose: To discuss the pharmacotherapeutic aspects of Mirabegron which is a first-inclassnovel β3 receptor agonist drug recently approved by the food and drug administration(FDA) for the treatment of overactive bladder (OAB).Materials and Methods: We ...
Mohammed Imran +2 more
doaj
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
Sacral neuromodulation in overactive bladder: a review and current perspectives
Troy Sukhu,1 Michael J Kennelly,2 Raj Kurpad1 1Department of Urology, University of North Carolina, Chapel Hill, 2Department of Urology, Carolinas Medical Center, Charlotte, NC, USA Abstract: Overactive bladder (OAB) symptoms of urgency, frequency, and ...
Kennelly MJ, Sukhu T, Kurpad R
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