Results 221 to 230 of about 44,395 (311)

Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of 18F‐Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3

ChemMedChem, Volume 20, Issue 24, December 15, 2025.
Fluorinated peptidomimetics targeting muscarinic acetylcholine receptor subtype M3: Fluorinated peptidomimetic compounds based on a β‐alanine‐glycine scaffold, with lead compound 24 demonstrating high M3 selectivity and submicromolar potency. The first M3‐selective positron emission tomography radioligand, [18F]24, is synthesized and will be evaluated ...
Miguel A. Herrera‐Rueda, Maxwell A. Boateng, Melinda Wuest, Frederick G. West, Frank Wuest   +4 more
wiley   +1 more source

Overactive Bladder and Its Impact on Everyday Life: A Qualitative Study. [PDF]

Cureus
Sigvard Fjord J, Thomsen T, Vahr Lauridsen S, Borgstrøm M.   +3 more
europepmc   +1 more source

Symptoms of overactive bladder (OAB) in patients treated for depressive disorders

, 2019
Michał Skalski, Mikołaj Przydacz, Jerzy A Sobański, Katarzyna Cyranka, Katarzyna Klasa, Wojciech Datka, Tomasz Gołąbek, Piotr Chłosta, Dominika Dudek   +8 more
openalex   +1 more source

Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway

The FASEB Journal, Volume 39, Issue 23, 15 December 2025.
SA treatment enhances functional recovery in murine spinal cord injury (SCI) models. Mechanistically, SA activates the Nrf2‐Keap1 pathway by disrupting the Keap1‐Nrf2 interaction, enabling Nrf2 nuclear translocation and phosphorylation. This triggers antioxidant responses that reduce reactive oxygen species (ROS).
Lü Ren, Yue Chen, Jinzhi Xia, Xue Song, Lu Tao, Jing Li, Lei Xu, Hezuo Lü, Jianguo Hu   +8 more
wiley   +1 more source

An updated meta-analysis of head-to-head trials comparing the efficacy, safety, and adherence of mirabegron and vibegron in overactive bladder. [PDF]

Medicine (Baltimore)
Bai WZ, Zhou SY, Mou YY, Peng L, Li LL.
europepmc   +1 more source

Overactive Bladder is a Distress Symptom in Heart Failure [PDF]

, 2018
Youn‐Jung Son, Bo-Eun Kwon
openalex   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Childhood Nocturnal Enuresis as a Risk Factor for Overactive Bladder in Young Adults. [PDF]

Acta Paediatr
Ito A, Akagawa S, Kato S, Tsuji S, Akagawa Y, Kaneko K.   +5 more
europepmc   +1 more source

Combined conservative interventions for urge, stress or mixed incontinence in adults [PDF]

, 2010
Abrams, Abrams, Andersson, Anger, Anger, Berghmans, Diokno, Dooley, Dumoulin, Eustice, Hay Smith, Monz, National Collaborating Centre for Women's and Children's Health, Nygaard, Ostaszkiewicz, Ostaszkiewicz, Shamliyan, Shaw, Subak, Temml, Tennstedt, Teunissen, Vandoninck, Wallace   +23 more
core   +1 more source

Overactive bladder [PDF]

Family Medicine and Community Health, 2013
Elizabeth Ferry, Firouz Daneshgari
openaire   +1 more source