Results 41 to 50 of about 44,395 (311)

Prevalence and risk factors for overactive bladder symptoms in patients with artificial urinary sphincter

Scientific Reports
To demonstrate the prevalence and risk factors for overactive bladder symptoms associated with artificial urinary sphincter implantation, we investigated the patients who underwent primary artificial urinary sphincter implantation with severe urinary ...
Hisanori Taniguchi, Nae Takizawa, Hidefumi Kinoshita   +2 more
doaj   +1 more source

Overactive bladder in males [PDF]

Therapeutic Advances in Urology, 2009
The prevalence of overactive bladder (OAB) symptoms is considerable in both men and women and the impact on quality of life (QOL) is equally substantial. Ironically, despite nearly equal prevalence, OAB symptoms in men are infrequently treated, and often with medical therapies aimed at bladder outlet obstruction (BOO).
Alex Gomelsky, Roger R. Dmochowski
openaire   +3 more sources

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

A review of studies mapping (or cross walking) from non-preference based measures of health to generic preference-based measures [PDF]

, 2008
This paper presents a systematic review of current practice in mapping between nonpreference based measures and generic preference-based measures.
Brazier, J.E., Tsuchiya, A., Yang, Y.
core   +2 more sources

Is urinary incontinence associated with sedentary behaviour in older women? Analysis of data from the National Health and Nutrition Examination Survey [PDF]

, 2020
BACKGROUND: Urinary incontinence (UI) is a common geriatric syndrome associated with physical and cognitive impairments. The association between type of UI and sedentary behaviour (SB) has not been explored. AIM: To determine association between moderate-
Booth, Joanne, Chastin, Sebastien F.M., Gine-Garriga, Maria, Hagen, Suzanne, Jerez-Roig, Javier, Skelton, Dawn A.   +5 more
core   +2 more sources

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

A Randomized Controlled Trial of Device Guided, Slow-Paced Respiration in Women with Overactive Bladder Syndrome. [PDF]

, 2019
PurposeWe evaluated the effects of device guided, slow-paced respiration on urgency associated urinary symptoms, perceived stress and anxiety, and autonomic function in women with overactive bladder syndrome.Materials and methodsWe performed a randomized,
Grady, Deborah, Hernandez, Cesar, Huang, Alison J, Mendes, Wendy B, Schembri, Michael, Subak, Leslee L   +5 more
core   +1 more source

Conservative interventions for urinary incontinence in women: an overview of Cochrane systematic reviews [PDF]

, 2016
This is the protocol for a review and there is no abstract. The objectives are as follows:  To synthesise Cochrane reviews of conservative interventions, as described above, for the prevention or treatment of female urinary incontinence.Output Type ...
Alewijnse, Alewijnse, Alhasso, Alves, Amaro, Balshem, Bastian, Berkman, Blaivas, Bogner, Bump, Bø, Cadwell, Carriere, Chaimani, Chang, Chiarelli, Clement, Cody, Dean, Dumoulin, Duthie, Eustice, Ford, Francis, French, Glazener, Glazener, Godec, Groat, Groat, Groutz, Guyatt, Guyatt, Guyatt, Guyatt, Guyatt, Guyatt, Guyatt, Hajebrahimi, Haylen, Herbison, Hunskaar, Hunskaar, Imamura, Islah, Jackson, Kelleher, Kirchin, Komesu, Lapitan, Lipp, MacArthur, McClurg, Melville, Messelink, Milsom, Morrill, Morrison, Ostaszkiewicz, Ostaszkiewicz, Palmer, Perry, Pollock, Rai, Rehman, Sandvik, Sandweiss, Shinohara, Smith, Takahashi, Thom, Turner, Wagner, Wallace, Wang, Whitford, Wilks, Wilson, Yau   +79 more
core   +3 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Barriers to early and effective overactive bladder management in male patients with lower urinary tract symptoms.

PLoS ONE
Overactive bladder is underdiagnosed and undertreated in men as symptoms overlap with benign prostatic obstruction. This study identified barriers urologists encountered in effectively managing overactive bladder in men with lower urinary tract symptoms.
Paul Rasner, Maria Arcila-Ruiz, José Ailton Fernandes Silva, Umaphorn Nuanthaisong, Sung Yung Cho, Eric Chung   +5 more
doaj   +1 more source