Results 71 to 80 of about 44,395 (311)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

Onabotulinumtoxin type A improves lower urinary tract symptoms and quality of life in patients with human T cell lymphotropic virus type 1 associated overactive bladder

Brazilian Journal of Infectious Diseases, 2018
Aim: To evaluate the efficacy of the onabotulinum toxin type A in the treatment of HTLV-1 associated overactive bladder and its impact on quality of life (QoL).
Jose Abraão Carneiro Neto, Silvane Braga Santos, Gloria Orge Orge, Davi Tanajura, Lucia Passos, Cassius José Oliveira, Rosana Andrade, Cláudio Galeno de Melo, Ubirajara Barroso, Jr, Edgar M. Carvalho   +9 more
doaj   +1 more source

A pilot study to measure dynamic elasticity of the bladder during urodynamics [PDF]

, 2017
AIMS: Previous studies using isolated strips of human detrusor muscle identified adjustable preload tension, a novel mechanism that acutely regulates detrusor wall tension. The purpose of this investigation was to develop a method to identify a correlate
Abrams, Almasri, Almasri, Colhoun, Coolsaet, Gupta, Kanai, Korkmaz, Landau, Metcalfe, Ockrim, Ratz, Rosier, Shiomi, Simeone, Smith, Sorensen, Southern, Speich, Speich, Speich, Wagg, Winters, Wyndaele, Young   +24 more
core   +3 more sources

Overactive bladder in children

Canadian Urological Association Journal, 2017
Overactive bladder (OAB) is a highly prevalent disorder in the pediatric population. This condition is especially troublesome for pediatric patients and their families when associated with incontinence, since it negatively affects self-esteem and impairs children’s development.
Sophie, Ramsay, Stéphane, Bolduc
openaire   +3 more sources

Video Urodynamic Study in Patients with Parkinson's Disease and Multiple System Atrophy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Most studies have analyzed the urodynamic characteristics of patients with Parkinson's disease (PD) and multiple system atrophy (MSA) using conventional urodynamic studies. Objectives This study investigated the urodynamic characteristics of both diseases using video urodynamic study (VUDS).
Hyun Sik Yoon, Seung Ho Jeon, Han‐Joon Kim, Seung‐June Oh   +3 more
wiley   +1 more source

Making Rasch decisions: the use of Rasch analysis in the construction of preference based health related quality of life instruments [PDF]

Objective: To set out the methodological process for using Rasch analysis alongside traditional psychometric methods in the development of a health state classification that is amenable to valuation.
Brazier, J, Coyne, K, Tsuchiya, A, Yang, Y, Young, Tracey A.   +4 more
core   +4 more sources

The binding of botulinum neurotoxins to different peripheral neurons [PDF]

, 2017
Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
core   +1 more source

Efficacy of TAC-302 for patients with detrusor underactivity and overactive bladder: a randomized, double-blind, placebo-controlled phase 2 study [PDF]

, 2022
Masaki Yoshida, Momokazu Gotoh, Osamu Yokoyama, Hidehiro Κakizaki, Tomonori Yamanishi, Osamu Yamaguchi   +5 more
openalex   +1 more source

Clinical and Radiological Evolution of Idiopathic Normal Pressure Hydrocephalus: A Critical Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The pathophysiology of idiopathic normal pressure hydrocephalus (iNPH) remains poorly understood. While it is commonly accepted that iNPH has an insidious onset, little is known about its preclinical and early stages and its development over time.
David Campo‐Caballero, Elissa Ash, Alfonso Fasano, Davide Martino, Mats Tullberg, Araceli Alonso Canovas, Joachim K. Krauss   +6 more
wiley   +1 more source

Exploring Overactive Bladder Symptoms in Premenopausal and Postmenopausal Women: A Comparative Cross-Sectional Study

Makara Journal of Health Research
Background: Overactive bladder syndrome affects millions globally. It can intermittently cause urinary incontinence, which can significantly diminish the quality of life.
Egemen Tural, Ayşe Deniz Ertürk Coşkun, Gizem Pınar, Fisun Vural   +3 more
doaj   +1 more source