Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Seasonal Mortality Patterns Analyzing Epidemiological Impact of COVID-19 on Overall Mortality Rates in Belgrade, Serbia Over Three-Year Period (2020-2023): Mental Health Consequences and Public Health Implications. [PDF]
J Clin MedMilic J +6 more
europepmc +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
CORR Insights®: Can Bisphosphonate Therapy Reduce Overall Mortality in Patients With Osteoporosis? A Meta-analysis of Randomized Controlled Trials. [PDF]
Clin Orthop Relat ResWebb ML.
europepmc +1 more source
Advanced Materials, EarlyView.The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena +10 more
wiley +1 more source
Positive Toxoplasma IgG Serology Is Associated with Increased Overall Mortality - A Propensity Score-Matched Analysis. [PDF]
Am J Trop Med HygMontalbano G +8 more
europepmc +1 more source
Advanced Materials Technologies, EarlyView.We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang +7 more
wiley +1 more source
Relationship Between the Lactate-to-Albumin Ratio and 28-Day Overall Mortality in Critically Ill Patients with Pulmonary Embolism: A Retrospective Analysis of the MIMIC-IV Database. [PDF]
Clin Appl Thromb HemostXu J, Wu S, Li H, Chen X, Zhou Y, Xu Y.
europepmc +1 more source
Advanced Materials Technologies, EarlyView.A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti +4 more
wiley +1 more source