Results 161 to 170 of about 1,649,429 (264)

Lymph node ratio and overall survival in patients with colon cancer: a prospective multicentre cohort study. [PDF]

Sci Rep
Ekman M, Jodłowska-Siewert E, Urbanowicz M, Berut M, Grabowski A, Kapturkiewicz B, Nycz M, Putko M, Szarmach A, Dudzic W, Jastrzębski T.   +10 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Circulating Lymphocyte Subsets Are Associated with Diabetic Kidney Disease and Overall Survival in Patients with Type 2 Diabetes. [PDF]

Biomedicines
Li G, Chen J, Xu C, He G, Yu F, Liu W, Wu Y, Hao W, Hu W.   +8 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Model-Based Meta-Analysis of Overall Survival in Vulnerable Platinum-Ineligible NSCLC Populations. [PDF]

CPT Pharmacometrics Syst Pharmacol
Chen J, Wada R, Zhang N, Graupner V, Morris S, Hu Y, Zhang W, Kassir N, Wu B, Chan P.   +9 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Preoperative Quality of Life as Predictor of Postoperative Early Recurrence and Overall Survival in Patients with Pancreatic and Periampullary Adenocarcinoma. [PDF]

J Gastrointest Cancer
Hansen CP, Plum LM, Storkholm JH, Pommergaard HC.   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Correction to: Survivorship in advanced ovarian cancer: a prognostic model for overall survival and risk of recurrence. [PDF]

Oncologist
europepmc   +1 more source

Evaluation of RECIST v1.1 for predicting overall survival in sarcoma patients with pulmonary metastasis. [PDF]

Cancer Imaging
Gold L, Klambauer K, Dascalescu C, Klinge L, Winkelmann M, Mansour N, Mehrens D, Ricke J, von Bergwelt-Baildon M, Di Gioia D, Lindner LH, Kunz WG.   +11 more
europepmc   +1 more source