Drone-Delivery Network for Opioid Overdose -- Nonlinear Integer Queueing-Optimization Models and Methods [PDF]
arXiv, 2022 We propose a new stochastic emergency network design model that uses a fleet of drones to quickly deliver naxolone in response to opioid overdoses. The network is represented as a collection of M/G/K queuing systems in which the capacity K of each system is a decision variable and the service time is modelled as a decision-dependent random variable ...
arxiv
Advanced Healthcare Materials, EarlyView.A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang +10 more
wiley +1 more source
Criminal Justice Faculty Expert Works with East Bridgewater Police on Initiative to Stem Opioid Epidemic, Shift to Treatment Model [PDF]
, 2016 Plymouth County, Mass., law enforcement officials enlist RWU Professor of Criminal Justice Sean Varano for assistance in developing new overdose-prevention ...
Rodrigues, Jill
core +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
Advanced Materials, EarlyView.We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin +17 more
wiley +1 more source
Preventing opioid overdoses in Europe:a critical assessment of known risk factors and preventative measures [PDF]
, 2012 This report is the outcome of a project into opioid overdoses. The remit was to focus on finding practical methods of overdose prevention. In order to fulfil this remit, a critical review of existing knowledge on overdose prevention was conducted.
Baldacchino, Alex +3 more
core +1 more source
Reducing drug related deaths : a pre-implementation assessment of knowledge,barriers and enablers for naloxone distribution through general practice [PDF]
, 2014 Peer reviewedPublisher ...
A McAuley +26 more
core +3 more sources
Advanced Materials, EarlyView.Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim +8 more
wiley +1 more source
Housing and overdose: an opportunity for the scale-up of overdose prevention interventions?
Harm Reduction Journal, 2017 Background North America is currently experiencing an overdose epidemic due to a significant increase of fentanyl-adulterated opioids and related analogs.
Geoff Bardwell +3 more
doaj +1 more source
Post-mortem Redistribution of Alprazolam in Rats
Prague Medical Report, 2020 The post-mortem toxicological findings may be misinterpreted, if the drug undergoes substantial post-mortem redistribution. As alprazolam is one of the most frequently evaluated drug for legal/forensic reasons in drug-related fatalities, we studied ...
Jana Hořínková +5 more
doaj +1 more source
Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
Advanced Materials, EarlyView.A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung +10 more
wiley +1 more source