Results 131 to 140 of about 128,386 (269)

Reversal, Risk, and Responsibility in the Era of Potent Opioids and Overdose. [PDF]

Anesthesiology
Rathmell JP, Kern SE.
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

The All-Payer Claims Database After the Gobeille Supreme Court Decision: Assessing the Impact on Fatal Opioid-Related Overdose Research. [PDF]

Health Serv Res
Cordes J, Bauer C, Bernson D, Larochelle MR, Li W, Cao J, Dammann O, Stopka TJ.   +7 more
europepmc   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Higher drug overdose mortality among non-hispanic black adults aged 55 and older in the U.S.: Analysis of national death records from CDC's WONDER database (1999-2023). [PDF]

Drug Alcohol Depend Rep
Li Z, Jin Y, Smith MK, Schackman BR, Crable EL, Behrends CN, Wagner K, Walley AY, Marshall BDL, Zang X.   +9 more
europepmc   +1 more source

Clinical and demographic characteristics of adolescents, emerging adults, and young adults presenting to an emergency department following a suicide attempt

JCPP Advances, EarlyView.
Abstract Introduction Suicide is a significant public health concern and the second leading cause of death in adolescents and young adults. This study sought to better understand differences in demographic and clinical characteristics of young people who attempted suicide during three phases of this developmental period: late adolescence (14–17 years),
Nicholas M. Brdar, Natasha K. Matta, Chloe A. Miner, Mubashshir R. Bhuiyan, Irmgard G. Pallas, Anna L. Bickersteth, Hailey G. Prokop, Lindsay A. Bornheimer   +7 more
wiley   +1 more source

Understanding the role of overdose witnesses: responses and characteristics of people who inject drugs in Oakland and San Francisco. [PDF]

Harm Reduct J
Suprasert B, Ruiz R, Francisco J, Lella P, O'Neal IR, Velasquez G, Baguso GN, Santos GM, Wilson EC, Dunne EF, McFarland W.   +10 more
europepmc   +1 more source

Patterns of help‐seeking for mental health problems in 1001 self‐identified neurodivergent adolescents who self‐harm

JCPP Advances, EarlyView.
Adolescents who self‐harm are also more likely to seek support from informal than formal sources and least likely to seek support online. But neurodivergent adolescents who self‐harm are more likely to seek any and especially formal (pastoral school staff or mental health services) support than their peers.
Simona Skripkauskaite, Galit Geulayov, the OxWell Study Team, Mina Fazel, Rohan Borschmann   +4 more
wiley   +1 more source

Variations in Poisoning Epidemiology and Management During the Initial COVID-19 Outbreak in a Taiwanese Emergency Department

International Journal of General Medicine
Lu-Chen Chen,1 Chih-Yang Mao,1 Chan-Wa Cheong,1 Wei-Chen Chen,1 Tzung-Hai Yen,2,3 Hsien-Yi Chen1,3 1Department of Emergency Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (R.O.C.); 2Department of Nephrology and Clinical Poison Center ...
Chen LC, Mao CY, Cheong CW, Chen WC, Yen TH, Chen HY   +5 more
doaj  

Understanding the Impact of Structural Racism and Violence Across the Lifespan on Overdose Vulnerability Among Black San Franciscans Experiencing Homelessness. [PDF]

J Psychoactive Drugs
Gourdet M, Koenders SL, Johnson NL, Jacques T, Coronado ZK, Augustine D, Taylor G, Knight KR, Bluthenthal R.   +8 more
europepmc   +1 more source