Results 171 to 180 of about 128,386 (269)

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

Examining the association between county racialised economic segregation and fatal overdose in US counties, 2018-2022. [PDF]

J Epidemiol Community Health
Doonan SM, Joshi S, Choi S, Adhikari S, Davis CS, Cerdá M.   +5 more
europepmc   +1 more source

Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedures. Study Design Retrospective cohort study. Setting TriNetX US Collaborative Research Network. Methods The
Michael Liu, Austin Lee, Salim Hayek, Shawn Li   +3 more
wiley   +1 more source

Health Plan Disenrollment and Mortality After Initiation of Medications for Opioid Use Disorder. [PDF]

JAMA Psychiatry
Nguyen AP, Binswanger IA, Narwaney KJ, Goodrich G, Christine PJ, Campbell CI, Xu S, Loree AM, Glanz JM.   +8 more
europepmc   +1 more source

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa, Debra Faulk, Vinicius Caldeira Quintao, Niekoo Abbasian, Hans D. de Boer, Ricardo Vieira Carlos   +5 more
wiley   +1 more source

Study protocol for a randomized trial examining a peer grief support approach for people grieving drug overdose deaths. [PDF]

Addict Sci Clin Pract
Osilla KC, Watkins KE, Lord T, Lord G, Cook F, Nameth K, Kim JP, Hawkins W, Athey A.   +8 more
europepmc   +1 more source

Organizing across cognitive asymmetry in human–AI collaboration: A study of perfume creation

Strategic Management Journal, EarlyView.
Abstract Research Summary As organizations increasingly adopt generative AI (GenAI), they face a strategic challenge: not only deciding which tasks AI should perform, but also how to organize the integration of human and AI efforts to produce viable solutions.
Tomoko Yokoi, Daniella Laureiro‐Martinez, Federico Magni, Stefano Brusoni   +3 more
wiley   +1 more source

Associations of Cannabis and Tobacco Use with Suicide Attempt, Suicide Death, and Overdose Death Among Veterans Prescribed Opioid Analgesics. [PDF]

Am J Prev Med
Nguyen N, Leonard S, Byers AL, Austin PC, Krebs EE, Sandbrink F, Bravata DM, Keyhani S.   +7 more
europepmc   +1 more source

Extrahepatic Gene Editing In Vivo Using Organic Solvent‐Free Lipid Nanoparticles

Small, EarlyView.
This article highlights a novel, organic solvent‐free lipid nanoparticle (LNP) formulation that avoids cholesterol, thereby reducing hepatic accumulation and immune activation. These BLNPs enable potent, flexible, and scalable gene delivery, supporting personalized medicine and diverse nucleic acid applications.
Michael Streiber, Na Liu, Laurianne Simon, Franziska Adermann, Vivien Bachmann, Lucas Gath, Stephanie Hoeppener, Stephanie Schubert, Oliver Werz, Vincent Lapinte, Marie Morille, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +14 more
wiley   +1 more source

High-dose insulin euglycaemic therapy for a severe calcium channel blocker overdose. [PDF]

BMJ Case Rep
Catarinella M, Endeman H.
europepmc   +1 more source