Results 211 to 220 of about 320,909 (424)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao +14 more
wiley +1 more source
Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal [PDF]
, 2018 This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with
Clark, Peter +12 more
core
Appraising the visibility, relevance and impacts of clinical pharmacology
British Journal of Clinical Pharmacology, EarlyView.Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers +5 more
wiley +1 more source
Forecasting Opioid Incidents for Rapid Actionable Data for Opioid Response in Kentucky [PDF]
arXivWe present efforts in the fields of machine learning and time series forecasting to accurately predict counts of future opioid overdose incidents recorded by Emergency Medical Services (EMS) in the state of Kentucky. Forecasts are useful to state government agencies to properly prepare and distribute resources related to opioid overdoses effectively ...
arxiv
British Journal of Clinical Pharmacology, EarlyView.Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan +3 more
wiley +1 more source
Severe peripheral neuropathy after mandrax overdose. [PDF]
, 1975 K Constantinidis
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza +26 more
wiley +1 more source
16 N-ACETYLCYSTEINE THERAPY OF CHILDHOOD ACETAMINOPHEN OVERDOSE [PDF]
, 1978 Barry H. Rumack +2 more
openalex +1 more source