Results 61 to 70 of about 270,274 (308)
Advanced Science, EarlyView.This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong +12 more
wiley +1 more source
Advanced Science, EarlyView.Neoeriocitrin enhances osteogenesis in hDPSCs and bone regeneration by targeting Beclin1 to inhibit ubiquitination‐mediated degradation, thereby stabilizing Beclin1 and increasing its protein abundance to activate autophagy. Abstract Human dental pulp stem cells (hDPSCs) are dental‐derived mesenchymal stem cells with robust multipotent differentiation ...
Yu Wu +9 more
wiley +1 more source
Enteric-coated aspirin overdose and gastric perforation. [PDF]
, 1975 R. J. Farrand +2 more
openalex +3 more sources
Combatting Opioid-Related Deaths in Rural Vermont Through Community Partnership [PDF]
, 2018 Substance abuse continues to be a public health crisis. With legislative changes and creation of MAT programming in Vermont, access to behavioral health services for substance abuse treatment has shifted community response and perceptions.
Waller, Brianna F
core +1 more source
Advanced Science, EarlyView.Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li +20 more
wiley +1 more source
Antidote application: an educational system for treatment of common toxin overdose [PDF]
, 2017 Poisonings account for almost 1% of emergency room visits each year. Time is a critical factor in dealing with a toxicologic emergency. Delay in dispensing the first antidote dose can lead to life-threatening sequelae.
Brusic, V. +4 more
core
Acute liver necrosis following overdose of paracetamol. [PDF]
, 1966 Diana Davidson, W. N. Eastham
openalex +1 more source
Advanced Science, EarlyView.Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu +11 more
wiley +1 more source
Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics
Advanced Science, EarlyView.Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan +12 more
wiley +1 more source
Death by Dealer: When Addicts Overdose, Should Dealers Be Charged with Murder? [PDF]
, 2015 The nation is currently in the throes of an epidemic of opiate addiction. More Americans now die from fatal opiate overdoses than from automobile accidents every year -- and the problem is especially pronounced in white suburban, exurban, and rural ...
Patrick Radden Keefe
core