Results 41 to 50 of about 163,036 (303)

Hydro‐ and Lipophilicity of Molecular‐Size‐Controlled Hydrogel Drug Carriers

Advanced Materials Technologies, EarlyView.
We investigate nano‐sized hydrogel drug carriers with tailored hydro‐ and lipophilicity. We design their encapsulation and structure‐forming capabilities and follow them in real time during fabrication using time‐resolved and in situ grazing incidence x‐ray scattering.
Elisabeth Erbes, Naireeta Biswas, Calvin J. Gavillet, Matthias Schwartzkopf, Krishnayan Basuroy, Qing Chen, Andrei Chumakov, Susann Frenzke, Marc Gensch, Korneliya Gordeyeva, Patrycja Kielb, Sonja Kirchner, Volker Körstgens, Peter Müller‐Buschbaum, Henrike M. Müller‐Werkmeister, Jan Rubeck, Sreevidya Thekku Veedu, Jose de Jesus Velazquez‐Garcia, Vivian Waclawek, Daniel Söderberg, Stephan V. Roth, Simone Techert   +21 more
wiley   +1 more source

Nifedipine overdose [PDF]

Clinical Cardiology, 1988
AbstractOverdose with 300 mg of nifedipine in a 54‐year‐old woman led to profound hypotension and reflex tachycardia. The patient was treated with intravenous fluids, calcium gluconate, and dopamine. Cardiac rhythm disturbances, hypoglycemia, and myocardial depression were not found. Recovery was rapid and uneventful. The clinical aspects of nifedipine
D, Whitebloom, J, Fitzharris
openaire   +2 more sources

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

New psychoactive substances (NPS) identified in Canada: Results of the online NPS survey (2020–2023)

Emerging Trends in Drugs, Addictions, and Health
Purpose and scope: New psychoactive substances (NPS) are a broad class of compounds that are typically designed to mimic illicit substances and circumvent legislative controls.
Sophie Rymill, Lexy Candler, Pavitra Ramachandran, Chantal Bacev-Giles, Raymond-Jonas Ngendabanka, Stephane Racine, Nancy He, Michelle Ross, Susantha Mohottalage   +8 more
doaj   +1 more source

Staying under the Radar? Immigration Effects on Overdose Deaths and the Impact of Sanctuary Jurisdictions

Societies, 2023
Growing political and public rhetoric claim that immigration has contributed to drug crime and the overdose crisis of the 21st century. However, research to date has given little attention to immigration–overdose relationships, and almost no work has ...
Kelly Pierce, Diana Sun, Ben Feldmeyer
doaj   +1 more source

Volatile substance abuse:fatal overdose with dimethylether [PDF]

, 2015
With all of the recent publicity over novel psychoactive substances it is easy to forget that other easily available intoxicants can be found. Dimethyl ether (DME), also known as methylether, is an extremely flammable volatile organic compound with ...
Maskell, P.D., Seetohul, L. Nitin, Seetohul, L. N., De Paoli, Giorgia, Seetohul, L.N., Maskell, Peter D., De Paoli, Giorgia; id_orcid, De Paoli, G.   +7 more
core   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Overdose prevention activities led by local public health departments, 2019–2023

Substance Abuse Treatment, Prevention, and Policy
Background Drug overdose deaths in the United States increased to historic levels in recent years, with provisional estimates indicating more than 111,000 deaths in the 12 months ending July 2023. In 2019, the Centers for Disease Control and Prevention’s
April Wisdom, Stephanie Haddad, Madhumita Govindu, Francis Higgins, Nikki Filion, Kate Sullivan, Cherie Rooks-Peck   +6 more
doaj   +1 more source

Patterns of health care utilization among people who overdosed from illegal drugs: a descriptive analysis using the BC Provincial Overdose Cohort

Health Promotion and Chronic Disease Prevention in Canada, 2018
Introduction: British Columbia (BC) declared a public health emergency in April 2016 in response to a rapid rise in overdose deaths. Further understanding of health care utilization is needed to inform prevention strategies for individuals who overdose ...
Michael C. Otterstatter, Alexis Crabtree, Sabina Dobrer, Brooke Kinniburgh, Salman Klar, Anthony Leamon, Jennifer May-Hadford, Christopher Mill, Mina Park, Andrew W. Tu, Lu Zheng   +10 more
doaj   +1 more source

Implementation and evaluation of interprofessional overdose review team recommendations following intentional or accidental overdose events [PDF]

Mental Health Clinician
Drug overdose death rates in the United States remain high despite efforts to mitigate this risk. Many communities and hospitals across the country have implemented overdose review teams, including local overdose fatality review teams or postoverdose ...
Monica Barrett, PharmD, BCPP, Sarah Kemerer, PharmD, Michelle Colvard, PharmD, BCPP   +2 more
doaj   +1 more source