Results 21 to 30 of about 128,386 (269)

Early intravenous lipid emulsion therapy for diphenhydramine overdose: a case report

Toxicology Communications, 2021
Diphenhydramine (DPH) is a lipophilic inverse agonist at the histamine receptor. Overdoses usually present with anticholinergic symptoms. Wide-complex tachycardia decompensating into cardiovascular collapse may occur in larger overdoses. Here we report a
Joseph Clemons, Arvinder Jandu, Brandon Stein, Michael A. Chary   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Opioid Education and Nasal Naloxone Rescue Kits in the Emergency Department

Western Journal of Emergency Medicine, 2015
Introduction: Emergency departments (EDs) may be high-yield venues to address opioid deaths with education on both overdose prevention and appropriate actions in a witnessed overdose.
Dwyer, Kristin , Walley, Alexander Y. , Langlois, Breanne K. , Mitchell, Patricia M. , Nelson, Kerrie P. , Cromwell, John, Bernstein, Edward   +6 more
doaj   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source

Facilitating access to supervised smoking facilities: a qualitative study

Harm Reduction Journal
Introduction The implementation of supervised smoking facilities (SSFs) as a harm reduction intervention has public health benefits for people who inhale drugs, but there are significant knowledge gaps surrounding the perspectives of SSF visitors and ...
Courteney Wettemann, Jeffrey Morgan, Tara Taylor, Ardina Boll, Scott Maxwell, Lindsey Richardson, Seonaid Nolan, Jenna van Draanen   +7 more
doaj   +1 more source

Physicians’ Self-Reported Knowledge and Behaviors Related to Prescribing Opioids for Chronic Pain and Diagnosing Opioid Use Disorder, DocStyles, 2020

AJPM Focus
Introduction: In 2016, the Centers for Disease Control and Prevention released the Guideline for Prescribing Opioids for Chronic Pain (2016 Centers for Disease Control and Prevention Guideline) to improve opioid prescribing while minimizing associated ...
Kathleen R. Ragan-Burnett, MSPH, C. Robinette Curtis, MD, Kristine M. Schmit, MD, Christina A. Mikosz, MD, Lyna Z. Schieber, MD, Gery P. Guy, Jr, PhD, Tamara M. Haegerich, PhD   +6 more
doaj   +1 more source

Patient Preference for Pain Medication in the Emergency Department Is Associated with Non-fatal Overdose History

Western Journal of Emergency Medicine, 2018
Introduction: Opioid overdose is a major public health problem. Emergency physicians need information to better assess a patient’s risk for overdose or opioid-related harms.
Lauren K. Whiteside, Jason Goldstick, Aaron Dora-Laskey, Laura Thomas, Maureen Walton, Rebecca Cunningham, Amy S.B. Bohnert   +6 more
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Patterns of health care utilization among people who overdosed from illegal drugs: a descriptive analysis using the BC Provincial Overdose Cohort

Health Promotion and Chronic Disease Prevention in Canada, 2018
Introduction: British Columbia (BC) declared a public health emergency in April 2016 in response to a rapid rise in overdose deaths. Further understanding of health care utilization is needed to inform prevention strategies for individuals who overdose ...
Michael C. Otterstatter, Alexis Crabtree, Sabina Dobrer, Brooke Kinniburgh, Salman Klar, Anthony Leamon, Jennifer May-Hadford, Christopher Mill, Mina Park, Andrew W. Tu, Lu Zheng   +10 more
doaj   +1 more source