Results 151 to 160 of about 1,514,926 (296)

CDC in action : 2018 response to the opioid crisis [PDF]

The opioid overdose epidemic is the public health crisis of our time, devastating families and communities across the United States. Over the past few years, U.S. life expectancy has declined, a trend largely driven by deaths from drug overdose. In 2017,

core  

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

Safety of and serological response to a new canine distemper‐parvovirus combination vaccine in domestic ferrets

Veterinary Record, EarlyView.
Abstract Background Pet ferrets are typically vaccinated against distemper using a canine multivalent vaccine despite the lack of relevant safety or efficacy data. Here, we investigate the safety of a novel live canine parvovirus type 2c (CPV‐2c) vaccine strain and the efficacy of the live Onderstepoort canine distemper virus (CDV) vaccine strain used ...
Jacqueline Pearce, Léon Peeters, Ellen Versmissen, David Sutton, Ian Tarpey   +4 more
wiley   +1 more source

Characterization of patients declining to participate in opioid overdose prevention clinical research in an emergency department setting. [PDF]

J Subst Use Addict Treat
Ward RC, Brigham G, Barth KS, Jennings LK, Papa CE, Smith AJ, Litwin AH, Haynes L, Matheson T, Sonne S, Heineck L, McClure EA.   +11 more
europepmc   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Changes in community health worker knowledge and perspectives following opioid overdose prevention and response training. [PDF]

Harm Reduct J
Hooten M, McEntee ML.
europepmc   +1 more source

Firearms as a Market‐Driven Epidemic: Potential Pathways to Reduce Preventable Firearm‐Related Harm in the United States

The Milbank Quarterly, EarlyView.
Policy Points For half a century, firearm‐related deaths and injuries have been endemic in the United States, with COVID‐19 contributing to a record high of 48,830 deaths in 2021, an epidemic rate increase. By 2023, national trends masked a significant 10‐fold difference in firearm‐related death rates among states.
ESZTER RIMÁNYI, JONATHAN D. QUICK, STEPHEN W. HARGARTEN, CHARLES C. BRANAS, SANDRO GALEA, NASON MAANI, JONATHAN LOWY, ZAIN HUSSAIN, NICHOLAS HOFFMANN   +8 more
wiley   +1 more source

Core State Injury Prevention Program [PDF]

Core SIPP supports health departments to identify and respond to existing and emerging injury threats.The Core State Injury Prevention Program (Core SIPP) is a cooperative agreement funded by CDC\u2019s National Center for Injury Prevention and Control ...

core  

Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform

The Milbank Quarterly, EarlyView.
Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD, LAURA DWYER‐LINDGREN, CHRISTOPHER J.L. MURRAY   +2 more
wiley   +1 more source

Prevalence of novel psychoactive substances in selected clinical urine specimens submitted for drug monitoring

Journal of Forensic Sciences, EarlyView.
Abstract Novel psychoactive substances (NPS) are compounds emerging as alternatives to more established drugs of abuse. They are constantly changing and being modified, which makes their detection difficult. The study objective was to determine the prevalence of NPS in selected clinical specimens. Deidentified urine specimen remnants were analyzed that
Jillian R. Neifeld, Theresa M. Meli, Sarah H. Bartock   +2 more
wiley   +1 more source