Results 201 to 210 of about 1,458,432 (308)

PAARH suppresses Kupffer cell phagocytosis to promote tumor liver metastasis by upregulating CD47. [PDF]

Cancer Cell Int
Li W, Wei Y, Lu R, Tan G, Lu X, Lin J, Tan C, Wei H, Deng C, Wei Z, Pu J.   +10 more
europepmc   +1 more source

CCND1 Protein Overexpression [PDF]

, 2020
openaire   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Consensus on Human Epidermal Growth Factor Receptor 2 Overexpression Testing in Pan-Tumor. [PDF]

Cancer Innov
Wang Z, Chen L, Rao W, Cao B, Cai M, Fan X, Ji Y, Li Y, Song Y, Sun Y, Sun Y, Wu C, Xia Q, Xi Y, Xue L, Yin R, Liang H, Ying J.   +17 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Cloning and Functional Analysis of the <i>SiMAPKKK17</i> Gene in Foxtail Millet (<i>Setaria italica</i>). [PDF]

Plants (Basel)
Xue X, Mu A, Yang F, Zhang J, Zhang S, Liu D, He L, Zhang L, Zhao Y, Zhang Y, Wang X.   +10 more
europepmc   +1 more source

THBS1 Overexpression Positive [PDF]

, 2020
openaire   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

BMAL1 attenuates myocardial infarction-induced fibrosis via suppressing p-SMAD3/SMAD3 in TGF-β1 pathway. [PDF]

Biochem Biophys Rep
Zhang D, Wang H, Gu Z, Zhang L, Hu Z, Wang Y.   +5 more
europepmc   +1 more source

NTRK1 Overexpression Positive [PDF]

, 2020
openaire   +1 more source