Results 41 to 50 of about 368,237 (276)

Overfitting in Synthesis: Theory and Practice (Extended Version) [PDF]

open access: yes, 2019
In syntax-guided synthesis (SyGuS), a synthesizer's goal is to automatically generate a program belonging to a grammar of possible implementations that meets a logical specification.
Millstein, Todd   +3 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Overfitting Avoidance as Bias [PDF]

open access: yesMachine Learning, 1993
Strategies for increasing predictive accuracy through selective pruning have been widely adopted by researchers in decision tree induction. It is easy to get the impression from research reports that there are statistical reasons for believing that these overfitting avoidance strategies do increase accuracy and that, as a research community, we are ...
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Embracing Noise and Error

open access: yesHungarian Studies Yearbook, 2019
In his article “Embracing Noise and Error”, Bálint L. Bálint argues that human society is going through a profound change as mathematical models are used to predict human behavior both on a personal level and on the level of the entire society.
Bálint Bálint L.
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Day-Ahead Electric Load Forecasting for the Residential Building with a Small-Size Dataset Based on a Self-Organizing Map and a Stacking Ensemble Learning Method

open access: yesApplied Sciences, 2019
Electric load forecasting for buildings is important as it assists building managers or system operators to plan energy usage and strategize accordingly.
Jaehyun Lee, Jinho Kim, Woong Ko
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Macroeconomic Predictions Using Payments Data and Machine Learning

open access: yesForecasting, 2023
This paper assesses the usefulness of comprehensive payments data for macroeconomic predictions in Canada. Specifically, we evaluate which type of payments data are useful, when they are useful, why they are useful, and whether machine learning (ML ...
James T. E. Chapman, Ajit Desai
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

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