Results 41 to 50 of about 271,775 (312)

Economic Growth Model with Fertility Incentives: A Theoretical Analysis Framework and Policy Simulation for China

Mathematics
This study presents an overlapping generation model to examine the impact of fertility incentive policies on economic growth in China, incorporating endogenous fertility, education, and technological advancement by integrating unified growth theory with ...
Lei He, Qin Wang
doaj   +1 more source

The Impact of Labor Income Tax Progressivity on the Fiscal Multipliers in the Context of the Fiscal Consolidation

Notas Económicas, 2020
Fiscal multipliers depend on several structural characteristics of each economy. In this study it is argued that labor income tax progressivity lowers the fiscal multipliers of fiscal consolidation programs.
Mariana Santos
doaj   +1 more source

Aging effects on consumption risk-sharing channels in European countries [PDF]

Zbornik radova Ekonomskog fakulteta u Rijeci : časopis za ekonomsku teoriju i praksu, 2018
This study tests the hypothesis that aging affects risk sharing via capital markets, federal governments, and credit markets. We apply the decomposition method to both simulated and European country data.
Jeongseok Song, Doojin Ryu
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Analysis of Local Stability for Discrete Lotka-Volterra Models

Semina: Ciências Exatas e Tecnológicas
This paper applies the stability theory of discrete systems to a predator–prey model with a specific structure, formulated directly in discrete time.
Francis Félix Cordova Puma, Mireya Mendiguren Mager   +1 more
doaj   +1 more source

The effects of transport infrastructure on regional economic development: A simulated spatial overlapping generations model with heterogenous skill

Journal of Transport and Land Use, 2012
As a result of public investment, lower freight transport costs tend to translate into lower local price indices and are associated with equilibria characterized by higher capital intensity, output and consumption.
Ioannis Tikoudis, Marcus Sundberg, Anders Karlström   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Mr. Hayek and the Classics: A Suggested Interpretation of the Business Cycle Theory in _Prices and Production_

Quarterly Journal of Austrian Economics, 2021
This paper endeavors to develop a modern theoretical underpinning of Friedrich August von Hayek’s business-cycle theory as published during the Great Depression in his book Prices and Production. According to Hayek, economic cycles are caused by monetary
Nils Herger
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source