Results 51 to 60 of about 303,071 (273)

A Trust Incentive-Driven Consensus Feedback Mechanism for Large-Scale Participatory Budgeting

open access: yesMathematics
Large-scale participatory budgeting (PB) lacks a mechanism for reconciling divergent resident preferences before project selection. Conventional consensus feedback mechanisms are difficult to deploy in this setting because anonymous ballots provide no ...
Sijia Fu, Ying Ji
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Synthetic disjoint and overlapping dynamic attributed networks with ground-truth information

open access: yes
1. Synthetic network 1: We use the synthetic benchmark DANCer to create 12 datasets with ten timestamps for attributed graphs with undirected edges that can change over time, where nodes are grouped into densely connected sets, relatively homogeneous ...
Marquez, R (via Mendeley Data)
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Fuzzy Clustering Based on Activity Sequence and Cycle Time in Process Mining

open access: yesAxioms
Clustering plays a vital role in process mining as it organizes complex event logs into meaningful groups, helping to identify common patterns, outliers, and inefficiencies.
Onur Dogan, Hunaıda Avvad
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Enhancing E-Commerce Customer Segmentation with Fuzzy C-Means Soft Clustering Probabilities

open access: yesJournal of Applied Informatics and Computing
Customer segmentation is of paramount importance in the e-commerce industry, enabling businesses to improve marketing strategies and customer engagement.
Muhamad Iqbal Januadi Putra   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Fuzzy-based Medical X-Ray Image Classification

open access: yesJournal of Medical Signals and Sensors, 2012
In this paper, a novel fuzzy scheme for medical X-ray image classification is presented. In this method, each image is partitioned into 25 overlapping subimages and then, we extracted the shape-texture features from shape and directional information of ...
Fatemeh Ghofrani   +3 more
doaj  

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