Results 61 to 70 of about 303,071 (273)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

OVERLAPPING MEMBERSHIPS INREGIONAL ECONOMICCOMMINITIES: A COMPARATIVE STUDY ON ETHIOPIA AND KENYA

, 2023
Primarily, the paper examines the existence of overlapping membership in the four AU recognized regional trading arrangements, namely CEN-SAD, IGAD, COMESA and EAC which Ethiopia and Kenya are involved in, and secondly, it examine the effect of overlapping membership on the success of African Regional Integrations (African Economic Commission).
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Alumni Memberships and Correspondence - May 18, 1966 [PDF]

, 1966
This black and white three page document features the Fort Hays Kansas State College alumni memberships. The first page is a roster of the lifetime memberships, and the second is a roster of annual memberships.
Fort Hays Kansas State College
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Formal Concept Analysis and machine learning for EEG-based neurological outcome classification after cardiac arrest

Array
Cardiac arrest remains one of the leading causes of death worldwide, and early prediction of neurological outcome is important to guide post-resuscitation treatment. Although electroencephalography (EEG) provides valuable prognostic information, clinical
Ľubomír Antoni, Štefan Puci, Matúš Semančík, Dominika Kotlárová, Manohar Gowdru Shridhara, Daniela Pillárová, Peter Eliaš, Ján Guniš, Stanislav Krajči, Ondrej Krídlo, Ľubomír Šnajder   +10 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

2015-2016 University Committee Memberships [PDF]

, 2015
University committee memberships list from the Faculty Senate of the University of Northern ...
University of Northern Iowa. Faculty Senate.
core   +1 more source

CAPOS: The bulge Cluster APOgee Survey

Astronomy & Astrophysics
Context. The inner Milky Way hosts overlapping stellar populations (bar–bulge, inner thin and thick disks, and halo), thus complicating population assignments along the line of sight.
Salgado Carolina, Villanova Sandro, Geisler Doug, Barrera Nicolás, Ardern-Arentsen Anke   +4 more
doaj   +1 more source