Results 41 to 50 of about 632,926 (384)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Jurnal Kedokteran Gigi Universitas Padjadjaran, 2022 ABSTRAK Pendahuluan: Proses karies gigi dan gigi yang telah dilakukan perawatan endodontik menyebabkan kehilangan substansi gigi sehingga lebih rentan terhadap fraktur.
Lydiawati Wibisono, Diani Prisinda
doaj +1 more source
Understanding the Properties of the BitTorrent Overlay [PDF]
, 2007 In this paper, we conduct extensive simulations to understand the properties of the overlay generated by BitTorrent. We start by analyzing how the overlay properties impact the efficiency of BitTorrent.
Barakat, Chadi +2 more
core +3 more sources
, 2008 Several overlay-based live multimedia streaming platforms have been proposed in the recent peer-to-peer streaming literature. In most of the cases, the overlay neighbors are chosen randomly for robustness of the overlay.
Asaduzzaman, Shah +2 more
core +3 more sources
Pattern-Related Visual Stress, Chromaticity, and Accommodation [PDF]
, 2010 PURPOSE. To investigate the impact of colored overlays on the accommodative response of individuals, with and without pattern- related visual stress (PRVS), a condition in which individuals manifest symptoms of perceptual distortion and discomfort when ...
Allen, Peter M +3 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
An introduction to overlay journals [PDF]
, 2010 An overlay journal performs all the activities of a scholarly journal and relies on structural links with one or more archives or repositories to perform its activities.
Brown, J.
core
SPAD: a distributed middleware architecture for QoS enhanced alternate path discovery [PDF]
, 2007 In the next generation Internet, the network will evolve from a plain communication medium into one that provides endless services to the users. These services will be composed of multiple cooperative distributed application elements.
Diaz, Michel +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source