Results 51 to 60 of about 516,688 (344)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Buildings, 2019 Non-destructive testing (NDT) and semi-destructive testing (SDT) have recently been more frequently used for the evaluation and condition assessment of concrete floors in various types of buildings.
Jacek Szymanowski
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Journal of Oral Research, 2019 The hybrid prosthesis is a very predictable treatment option that allows patients to recover their oral functionality. It is a good alternative to conventional treatments and overdentures.
Roxana Contreras +2 more
doaj +1 more source
RIOJA (Repository Interface to Overlaid Journal Archives) project: final report [PDF]
, 2008 RIOJA (Repository Interface to Overlaid Journal Archives) was a 18-month partnership between UCL (University College London), Imperial College London, and the Universities Glasgow, Cambridge and Cornell.
Lewis, A., Moyle, M.
core
The Diverse Neuromuscular Spectrum of VPS13A Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger +16 more
wiley +1 more source
Cloud-network coordination service and application for telecom operators
Dianxin kexue, 2018 Coordination and innovation of cloud-network will become the differentiated competitive advantage of telecom operators,the integration innovation based on the existing cloud network soltions will be the basic,and the business innovation of cloud-network ...
Tian CHEN +4 more
doaj
ANALYSIS OF FLOOD PRONE AREAS IN NAGAN RAYA REGENCY ACEH PROVINCE
Malaysian Journal of Computing, 2020 Maps or remote sensing can be interpreted as the process of reading using various sensors where data collected remotely can be analyzed to obtain information about the object, area or phenomenon.
Amsar Yunan
doaj +1 more source