Results 51 to 60 of about 632,926 (384)
JXTA-Overlay: a P2P platform for distributed, collaborative, and ubiquitous computing [PDF]
, 2011 With the fast growth of the Internet infrastructure and the use of large-scale complex applications in industries, transport, logistics, government, health, and businesses, there is an increasing need to design and deploy multifeatured networking ...
Barolli, Leonard, Xhafa Xhafa, Fatos
core +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A Many-Core Overlay for High-Performance Embedded Computing on FPGAs [PDF]
, 2014 In this work, we propose a configurable many-core overlay for high-performance embedded computing. The size of internal memory, supported operations and number of ports can be configured independently for each core of the overlay.
Neto, Horácio, Véstias, Mário
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
IoT IP Overlay Network Security Performance Analysis with Open Source Infrastructure Deployment
Journal of Cybersecurity and PrivacySome of the most deployed infrastructures nowadays are Overlay Networks (ONs). They consist of hardware and software components designed to establish private and secure communication channels, typically over the Internet.
Antonio Francesco Gentile +3 more
doaj +1 more source
Synergistic Modern Global 1 Km Cropland Dataset Derived from Multi-Sets of Land Cover Products
Remote Sensing, 2019 The quality of global cropland products could affect our understanding of the impacts of cropland reclamation on global changes. With the advancement of remote sensing technology, several global land cover products and synergistic datasets have been ...
Chengpeng Zhang +4 more
doaj +1 more source
Small-world networks, distributed hash tables and the e-resource discovery problem [PDF]
, 2010 Resource discovery is one of the most important underpinning problems behind producing a scalable, robust and efficient global infrastructure for e-Science.
Hawick, K.A., Leist, A.
core
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source