Results 221 to 230 of about 746,175 (357)

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Iron overload is associated with increased susceptibility to pulmonary Pythium insidiosum infection in mice. [PDF]

PLoS Negl Trop Dis
Zhu D, Yan L, Sun J, Chen S, Xi Y, Zhang K, Li M.   +6 more
europepmc   +1 more source

Iron overload [PDF]

Postgraduate Medical Journal, 1969
openaire   +2 more sources

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Alpha-lipoic acid attenuates iron-overload-induced structural changes in the liver of the laboratory mouse (Mus musculus)

, 2018
William Sibuor, Fidel Gwala, Jeremiah Munguti, Moses Obimbo   +3 more
openalex   +2 more sources

A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells

Advanced Science, EarlyView.
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong, Ziwei Zhang, Ao Li, Ting Sun, Yunzhao Wu, Devkee M. Vadukul, Dylan Jones, Bing Li, Fengjie Liu, Francesco A. Aprile, Yuri Korchev, Julia Gorelik, David Klenerman, Andrew Shevchuk   +13 more
wiley   +1 more source

Analysis Of Factors Affecting The Effectiveness Of Handling Over-Dimension And Overloading (Odol) In East Java At Uppkb Trosobo Sidoarjo And Uppkb Singosari Malang

, 2023
I Made Buda Atmajaya, Haris Muhammadun, Wateno Oetomo   +2 more
openalex   +2 more sources

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Negative impact of very mild volume overload on the heart function in patients on chronic hemodialysis. [PDF]

Ren Fail
Michalickova K, Malik J, Valerianova A, Hruskova Z, Bednarova V, Lopot F, Buryskova Salajova K, Hladinova Z, Vychodilova T, Pesickova SS, Rocinova K, Tothova M, Szonowska B, Kratochvilova M, Kaiserova L, Janakova S, Tesar V.   +16 more
europepmc   +1 more source

SYSTEM ANALYSIS OF A MULTIPHASE QUEUEING SYSTEM WITH FLOW MERGING: SIMULATION MODEL AND NODE OVERLOAD ASSESSMENT

Olena Liubymenko, Oleksandr Stepa, Nataliya Maslova   +2 more
openalex   +1 more source