Results 71 to 80 of about 426,067 (292)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Core Challenges of Autism. Sensory aspects of autism

open access: yesАутизм и нарушение развития, 2016
An american clincal psychologist Bill Nason tells us about the differences in ways of functioning between people on the autistic spectrum and neurotypical people.
Nason William
doaj   +1 more source

Development of a mathematical model of cross-docking technology in railway warehouses [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета, 2018
To date, there is a steady trend of growth in the volume of carriage of packaged goods, the main cause of which is the accelerated development of small and medium-sized businesses.
Urmanova Z.A.
doaj   +1 more source

Antecedents and Consequences of Information Overload in the COVID-19 Pandemic

open access: yesInternational Journal of Environmental Research and Public Health, 2020
The global outbreak of coronavirus disease (COVID-19) in 2020 has significantly affected the information environment as well as the daily life of individuals across the world, with information about COVID-19 dominating all media channels. The information
Hyehyun Hong, H. Kim
semanticscholar   +1 more source

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

open access: yesAdvanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park   +23 more
wiley   +1 more source

Finite Element Analysis on Stress Development in Alveolar Bone During Insertion of a Novel Dental Implant Design

open access: yesApplied Sciences
A novel macrodesign for a dental implant characterized by a non-monotonic variation in core diameter and thread shape has been described to produce lower stress levels during insertion as compared to conventional tapered implants.
Ning Zhang, Matthias Karl, Frank Wendler
doaj   +1 more source

Job demands and job resources in the ministry

open access: yesSA Journal of Human Resource Management, 2009
The objective of this study was to investigate ministers’  job demands and  job resources using a qualitative design (n = 9). Fifteen themes emerged from the interviews.
Chenell Buys, Sebastiaan Rothmann
doaj   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch   +13 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Relación entre la Expansión de los Informes Publicados por las Empresas y la Calidad de las Decisiones de los Usuarios. El Problema de la Sobrecarga de Información.

open access: yesRevista de Contabilidad: Spanish Accounting Review, 2000
El énfasis en la provisión de toda aquella información relevante para los procesos de decisión de los usuarios está dando lugar a la presentación de informes tan amplios que pueden sobrecargar al individuo y deteriorar sus procesos de decisión.
María Flora Muíño Vázquez
doaj  

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