Results 81 to 90 of about 907,993 (350)

The myosin activator omecamtiv mecarbil improves wall stress in a rat model of chronic aortic regurgitation

open access: yesPhysiological Reports, 2021
In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction.
Bachar El Oumeiri   +8 more
doaj   +1 more source

Optimal routing on complex networks

open access: yes, 2006
We present a novel heuristic algorithm for routing optimization on complex networks. Previously proposed routing optimization algorithms aim at avoiding or reducing link overload. Our algorithm balances traffic on a network by minimizing the maximum node
B. Fortz   +5 more
core   +1 more source

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy. [PDF]

open access: yes, 2015
The low molecular weight protein tyrosine phosphatase (LMPTP), encoded by the ACP1 gene, is a ubiquitously expressed phosphatase whose in vivo function in the heart and in cardiac diseases remains unknown.
Al-Habeeb, Waleed   +20 more
core   +2 more sources

Is boredom proneness related to social media overload and fatigue? A stress-strain-outcome approach

open access: yesInternet Research, 2020
PurposeSocial media overload and fatigue have become common phenomena that are negatively affecting people's well-being and productivity. It is, therefore, important to understand the causes of social media overload and fatigue.
E. Whelan   +2 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Stresses in silos: Comparison between theoretical models and new experiments

open access: yes, 1999
We present precise and reproducible mean pressure measurements at the bottom of a cylindrical granular column. If a constant overload is added, the pressure is linear in overload and nonmonotonic in the column height. The results are {\em quantitatively}
A. V. Tkachenko   +33 more
core   +1 more source

Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause [PDF]

open access: yes, 2014
Background: Metabolic syndrome is characterized by the association of 3 or more risk factors, including: abdominal obesity associated with an excess of abdominal fat, insulin resistance, type 2 diabetes, dyslipidemia and hypertension.
Bernardes, Nathalia   +8 more
core   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Cruciform specimens used for determination of the influence of T-stress on fatigue crack growth with overloads on aluminum alloy Al 6061 T651

open access: yesFracture and Structural Integrity, 2019
The publication presents a cruciform specimen for the determination of cyclic crack growth data under biaxial loading. The design of the specimen with slotted loading arms allows good decoupling between the two loading directions.
Sebastian Henkel   +4 more
doaj  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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