Results 71 to 80 of about 907,993 (350)

Overload protection system for power inverter [PDF]

open access: yes, 1977
An overload protection system for a power inverter utilized a first circuit for monitoring current to the load from the power inverter to detect an overload and a control circuit to shut off the power inverter, when an overload condition was detected. At
Nagano, S.
core   +1 more source

Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis [PDF]

open access: yes, 2018
Osteoporosis is associated with chronic iron overload secondary to hereditary hemochromatosis (HH), but the causative mechanisms are incompletely understood.
Camacho, António   +7 more
core   +4 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure. [PDF]

open access: yes, 2019
Mice were treated with a fully human monoclonal glucagon receptor antagonistic antibody REMD2.59 following myocardial infarction or pressure overload.
Baal, Ulysis   +8 more
core  

Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Objective: Iron overload is common in elderly people which is associated with an increased prevalence of osteoarthritis (OA), but the exact role of iron in the development of OA has not been established.
Xingzhi Jing   +8 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Bismuth coordination networks containing deferiprone: synthesis, characterisation, stability and antibacterial activity [PDF]

open access: yes, 2015
A series of bismuth–dicarboxylate–deferiprone coordination networks have been prepared and structurally characterised. The new compounds have been demonstrated to release the iron overload drug deferiprone on treatment with PBS and have also been shown ...
An   +28 more
core   +2 more sources

Applying the SOBC paradigm to explain how social media overload affects academic performance

open access: yesComput. Educ., 2020
Research suggests University students are more disposed than others to develop problematic social media use. Social media overload, the phenomenon where users are exposed to a massive amount of information and communication demands via social media that ...
E. Whelan, A. Islam, Stoney L. Brooks
semanticscholar   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Implementasi Load Balancing Pada Web Server Menggunakan Nginx

open access: yesJurnal Teknologi dan Manajemen Informatika, 2020
Kebutuhan internet mempengaruhi pengunjung website semakin meningkat dan membuat beban traffic meningkat pada server, semakin banyak jumlah traffic ke server bisa menyebabkan web server menjadi down, jika digunakan dengan jumlah berlebih (overload ...
Fahmi Apriliansyah   +2 more
doaj   +1 more source

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