Results 81 to 90 of about 768,505 (310)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Constitutional control work of the executive authority comparative study with the Lebanese legislation [PDF]

open access: yesمجلة الاجتهاد للدراسات القانونية والاقتصادية, 2019
The acts of the executive authority are administrative acts issued by the president of the republic or by the Prime Minister. These include orders and decrees which are subject to appeal or notice thereof.
Ilyes Djouadi
doaj  

Current practice and perspectives in CRO oversight for Biostatistics & Data Management services – survey performed among members of the German Association of Research-Based Pharmaceutical Companies (vfa)

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie, 2018
Outsourcing of activities is common and increasing in the pharmaceutical industry, not only for clinical trial conduct, or other trial related aspects but also for biostatistics and data management.
Hennig, Michael   +5 more
doaj   +1 more source

A Copernican View of Health Care Antitrust [PDF]

open access: yes, 2002
Sage and Hammer use the analogy of Copernican astronomy to suggest that understanding the dramatic change wrought by managed care requires a conceptual reorientation regarding the meaning of competition in health care and its appropriate legal and ...
Hammer, Peter J., Sage, William M.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Legal mechanisms of audit and accountability in artificial intelligence systems in the context of international law

open access: yesНауковий вісник Ужгородського національного університету. Серія Право
This article is devoted to the oversight of AI systems’ activities and the provision of accountability obligations within the framework of international legal norms.
V.A. Afgan
doaj   +1 more source

Nanotechnology Oversight: An Agenda for the New Administration [PDF]

open access: yes, 2008
Identifies how current laws can be applied or modified to provide needed oversight of nanotechnology and materials for public health and environmental protection.
J. Clarence Davies
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Making Public Finance Public: Subnational Budget Watch in Croatia, Macedonia, and Ukraine [PDF]

open access: yes
This paper deals with issues of budgetary oversight and accountability in the field of secondary education. Based on the case of Ukraine, the paper analyzes the state of general budgetary oversight on the local level and goes into detail concerning ...
Katarina Ott, Sergii Slukhai
core  

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