Results 101 to 110 of about 768,505 (310)

Impact of the Human Genome Project at the Interface between Patent and FDA Laws [PDF]

open access: yes, 1996
Mr. Cunningham stresses the broad scope of biotechnological innovations. Besides endorsing the need for a new oversight commission to deal with potential social issues, he suggests, for example, that some products should be treated like biologics rather ...
Cunningham, Brian C.
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Never-Ending Story of PNR Profiling and Surveillance of Movement in the EU

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2026 11(1), 533-561 | Article | (Table of Contents) 1. Introduction – 2. The EU PNR Directive: a historical background and main elements – 3.
Elif Mendos Kuşkonmaz
doaj   +1 more source

Platform oversight

open access: yes, 2022
Verfassungsblog: On Matters ...
openaire   +2 more sources

Does Partisan Heritage Matter? The Case of the Federal Reserve [PDF]

open access: yes
Received evidence suggests that changes in appointer- and overseer- preferences influence monetary policy (i.e., partisan heritage matters). Evidence presented here, on the other hand, is consistent with changes in the cost of pursuing a common ...
Dino Falaschetti
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Legislative Oversight of Administrative Rulemaking in New Hampshire [PDF]

open access: yes, 1990
This paper explains how administrative rules are made in a small state. It also analyzes the role of a joint legislative committee which oversees the process and concludes that such oversight generally increases opportunities for public scrutiny of rules
Eaton, Scott F.
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Analysis of Flexural Bearing Capacity of Concrete Box Girders Reinforced with CFRP Mesh End Anchors

open access: yesZhongwai Gonglu
Carbon fiber reinforced polymer (CFRP) composites have significant advantages in the reinforcement of concrete structures. It is worth systematically studying the effect and mechanism of applying this material in embedded end-anchored reinforcement of ...
HU Guihua
doaj   +1 more source

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