Results 71 to 80 of about 464,209 (312)

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Overweight/obesity and respiratory and allergic disease in children: international study of asthma and allergies in childhood (ISAAC) phase two. [PDF]

, 2014
BACKGROUND: Childhood obesity and asthma are increasing worldwide. A possible link between the two conditions has been postulated. METHODS: Cross-sectional studies of stratified random samples of 8-12-year-old children (n = 10 652) (16 centres in ...
Forastiere, Francesco, Forastiere, F, Jaensch, A., Nagel, G, Jaensch Andrea, David P. Strachan, Gudrun Weinmayr (669480), Forastiere Francesco, Büchele Gisela, Strachan, D.P., Weinmayr, Gudrun, Gabriele Nagel (276147), Büchele, Gisela, Nagel, Gabriele, Gabriele Nagel, Jaensch, Andrea, Andrea Jaensch, Weinmayr Gudrun, Gisela Büchele, David P. Strachan (110302), Strachan, David P., Nagel Gabriele, Weinmayr, G, Strachan, DP, Andrea Jaensch (567644), Gudrun Weinmayr, Gisela Büchele (567645), David P Strachan, Weinmayr, G., Francesco Forastiere (669481), Strachan David P., ISAAC Phase Two Study Group, Büchele, G., Forastiere, F., Strachan, David P, Büchele, G, Jaensch, A, Francesco Forastiere, Nagel, G.   +38 more
core   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Prevalence of overweight, obesity and thinness in 9-10 year old children in Mauritius.

, 2012
OBJECTIVE: To document the prevalence of overweight, obesity and thinness in 9-10 year old children in Mauritius. METHODS: 412 boys and 429 girls aged 9-10 years from 23 primary schools were selected using stratified cluster random sampling. All data
Siegel, KR, Whincup, Peter H, Echouffo-Tcheugui, JB, Whincup, PH, Richards Nigel, Rudnicka, AR, Alicja R Rudnicka, Justin B Echouffo-Tcheugui, Rudnicka, Alicja R, Rudnicka Alicja R, Whincup Peter H, Caleyachetty, Rishi, Siegel, Karen R, Richards, N, Caleyachetty, R, Caleyachetty Rishi, Rishi Caleyachetty, Siegel Karen R, Karen R Siegel, Echouffo-Tcheugui Justin B, Nigel Richards, Richards, Nigel, Peter H Whincup, Echouffo-Tcheugui, Justin B   +23 more
core   +2 more sources

Regional differences in overweight: an effect of people or place?

, 2008
Objective: To examine UK country and English regional differences in childhood overweight (including obesity) at 3 years and determine whether any differences persist after adjustment for individual risk factors.
Law, C., Hawkins, S.S., Millennium Cohort Study Child Health Group, The, Dezateux, C., Griffiths, L.J., Cole, T.J.   +5 more
core  

Overweight and obesity in urban Africa: A problem of the rich or the poor? [PDF]

, 2009
BACKGROUND: Obesity is a well recognized risk factor for various chronic diseases such as cardiovascular diseases, hypertension, and type 2 diabetes mellitus.
Abdhalah K Ziraba, Ziraba Abdhalah K, Fotso, Jean C, Jean C Fotso, Ziraba, Abdhalah K, Fotso Jean C, Rhoune Ochako, Ochako, Rhoune, Ochako Rhoune   +8 more
core   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Health-related quality of life in overweight German children and adolescents: do treatment-seeking youth have lower quality of life levels? Comparison of a clinical sample with the general population using a multilevel model approach

, 2013
Finne E, Reinehr T, Schaefer A, Winkel K, Kolip P. Health-related quality of life in overweight German children and adolescents: do treatment-seeking youth have lower quality of life levels?
Anke Schaefer, Finne, Emily ; https://orcid.org/, Emily Finne, Kolip, Petra ; https://orcid.org/, Winkel, Katrin, Thomas Reinehr, Reinehr, Thomas, Schaefer, Anke, Petra Kolip, Katrin Winkel   +9 more
core   +2 more sources

Artificial Intelligence‐Based Body Composition Analysis Reveals Sex‐Specific Prognostic Markers and Their Clinical Value in Gastric Cancer: A Multicenter Study

Advanced Science, EarlyView.
This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li, Tingting Liu, Qian Yang, Zhiqing Zhang, Xiaofang Guo, Xiang Wang, Yihan Zhang, Limin Ge, Yu Su, Wenjun Wu, Weihua Guo, Zheng Wang, Lian Yang, Yanfeng Niu   +13 more
wiley   +1 more source