Results 81 to 90 of about 202,733 (250)

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

open access: yesAdvanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang   +7 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

open access: yesAdvanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang   +7 more
wiley   +1 more source

Overweight in Adolescents: Implications for Health Expenditures [PDF]

open access: yes
We consider two compelling research questions raised by the increased prevalence of overweight among adolescents. First, what factors explain variation in adolescent bodyweight and the likelihood of being overweight? Next, do overweight adolescents incur
Alan C. Monheit   +2 more
core  

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

open access: yesAdvanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song   +9 more
wiley   +1 more source

Assessing community readiness for overweight and obesity prevention in pre-adolescent girls:a case study [PDF]

open access: yes, 2013
Childhood overweight and obesity is a global public health concern. For girls in particular, being overweight or obese during pre-adolescence (aged 7-11 years) has intergenerational implications for both the mother and her future offspring. In the United
Kesten, Joanna May   +5 more
core   +2 more sources

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

open access: yesAdvanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu   +16 more
wiley   +1 more source

Examination of Gender Differences: Causal Attributions of Treatment-Seeking Individuals With Overweight and Obesity

open access: yesClinical Psychology in Europe
[Background] Addressing patients' perceptions of the causes of their overweight and obesity may be a promising approach to enhance treatment motivation and success. Previous research suggests that there are gender differences in these aspects.
Carmen Henning   +6 more
doaj   +1 more source

The Income Gradient and Distribution-Sensitive Measures of Overweight in the U.S. [PDF]

open access: yes
This paper considers alternate measures of overweight in the U.S. that are sensitive to changes in the body-mass index (BMI) distribution, more robust to measurement error and continuous in the body-mass index (BMI) at the overweight threshold.
Jolliffe, Dean
core  

Modifiable early-life risk factors for childhood adiposity and overweight: an analysis of their combined impact and potential for prevention [PDF]

open access: yes, 2015
Background: early life may be a “critical period” when appetite and regulation of energy balance are programmed, with lifelong consequences for obesity risk.
Crozier, Sarah   +15 more
core   +1 more source

Improving the Physicochemical Properties, Organic Acids, Amino Acids, Volatile Organic Compounds, and Metabolites of Laohan Melon Juice Through Fermentation With Different Lactic Acid Bacteria

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermentation with lactic acid bacteria could improve amino acids, volatile organic compounds (VOCs), and nonvolatile metabolites of Laohan melon juice (LMJ), which provides theoretical guidance for the development of Laohan melon beverage and advances knowledge of the metabolic mechanisms of VOCs in LMJ.
Yun Xie   +12 more
wiley   +1 more source

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