Results 61 to 70 of about 65,099 (252)

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

Epilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan   +18 more
wiley   +1 more source

Publij Ovidij Nazon: Metamorfoze 10–12

Keria: Studia Latina et Graeca, 2018
Skozi neznanski se eter v žafranastem plašču odpravil potlej Himén je; urezal je pot v deželo Kikoncev, kamor ga Orfejev glas zaman je vabil in klical.
Joža Lovrenčič
doaj   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

Sleep Health in Bulimia Nervosa: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Research on sleep in bulimia nervosa (BN) is methodologically varied and yields inconsistent findings. This review synthesised BN‐sleep studies and examined whether comorbid mood disorders contribute to sleep disturbance. Method PsycINFO, Medline (Ovid), and Scopus were searched for English or French quantitative studies comparing ...
Samantha Kenny, Malka Hershon, Linda Booij, Rebecca Burdayron, Marie‐Hélène Pennestri   +4 more
wiley   +1 more source

Exploring the Effects of Frailty and Sarcopenia on Dysphagia in Head and Neck Cancer: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Frailty and sarcopenia may influence head and neck cancer (HNC) treatment outcomes, including dysphagia. Current understanding of this relationship, however, remains limited. This scoping review aimed to synthesize existing evidence on the relationship between frailty and/or sarcopenia and dysphagia in adults with HNC.
Rishni Perera, Elizabeth C. Ward, Nicole O'Donnell, Paul Yates, Rebecca L. Packer   +4 more
wiley   +1 more source

Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou, Pooja D. Reddy, Purva H. Rumde, Mary L. Klem, Sagar G. Kansara, Oldrich Virag, Yvonne M. Mowery, Nicole N. Scheff, Matthew E. Spector, Shaum Sridharan, Marci L. Nilsen, Kevin J. Contrera   +11 more
wiley   +1 more source

Validated Ovid Medline Search Assessment Tool

MedEdPORTAL, 2011
Introduction The ability to successfully search Medline and other online databases is a critical component to sustain lifelong learning among health care professionals.
Gurpreet Rana, Doreen Bradley, Monica Lypson   +2 more
doaj   +1 more source

Current Evidence on Best Practice Dental Survivorship Care for People With Head and Neck Cancer: An Overview of Systematic Reviews and Emerging Evidence

Head &Neck, EarlyView.
ABSTRACT Introduction Head and neck cancer (HNC) survival is improving, increasing the need to address long‐term survivorship issues. Dental survivorship—care before, during, and after treatment—remains inconsistent across services. We conducted a review of systematic reviews and emerging evidence to inform contemporary dental survivorship care for HNC
David G. Tighe, Rebecca Venchiarutti, Isidoro Ruisi, Purnima Sundaresan   +3 more
wiley   +1 more source

Pathogenic PPP2R5D variants disrupt neuronal development and neurite outgrowth in patient-derived neurons that are reversed by allele-specific knockdown

HGG Advances
Summary: A significant barrier to the treatment of neurodevelopmental disorders (NDDs) is a limited understanding of disease mechanisms. Heterozygous missense variants in PPP2R5D cause Houge-Janssens syndrome 1, a rare NDD characterized by macrocephaly ...
Randee E. Young, Michael V. Zuccaro, Charles A. LeDuc, Noelle D. Germain, Tae Hyun Kim, Patrick Sarmiere, Wendy K. Chung   +6 more
doaj   +1 more source