Results 111 to 120 of about 27,921 (258)

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li   +13 more
wiley   +1 more source

The Development of the Human Female Reproductive Tract. Part 1: Uterine Tube and Uterus

open access: yesClinical Anatomy, Volume 39, Issue 1, Page 92-111, January 2026.
ABSTRACT The uterine tubes and uterus develop from the paramesonephric (Müllerian) ducts. Most experimental data are obtained in rodents. Since the (micro‐)anatomy of the murine urogenital tract differs from that in humans, evaluation of the translatability of mouse data to human development is relevant.
Cindy J. M. Hülsman   +4 more
wiley   +1 more source

Novel Worker‐Like Behavior Observed in Gynes of the Social Parasite Tetramorium microgyna

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
Our article reports, to our knowledge, the first observations of inquiline gynes performing worker tasks for their host colony. We dissected these gynes to establish that they were all unmated. We hypothesize that nest excavation by social parasites represents an artifact of a non‐parasitic past.
François Brassard, Christina Kwapich
wiley   +1 more source

Sterol Metabolism in Ovariectomized Rats: Potential Roles of Campesterol and 4β‐Hydroxycholesterol in Osteoporosis

open access: yesLipids, Volume 61, Issue 1, Page 151-162, January 2026.
ABSTRACT Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue. Lipid metabolism disorders may contribute to osteoporosis in postmenopausal women. Phytosterols and oxysterols (OC) are involved in lipid metabolism.
Wenzhao He   +4 more
wiley   +1 more source

Structure of the disulfide‐rich modules of a striking tandem repeat protein, avian cysteine‐rich eggshell membrane protein

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract Avian eggshell membrane (ESM) is fabricated within the isthmus region of the oviduct and is comprised of three juxtaposed, predominantly proteinaceous layers lying between egg white and the calcified shell. The limiting membrane is less than 0.5 μm in thickness and forms the osmotic barrier for the egg. This first layer provides the foundation
Somayeh Zeinalilathori   +6 more
wiley   +1 more source

Development, Live Birth and Fertility in Mouse Oocytes Penetrated by Spermatids Exposed to the HDAC Inhibitor Scriptaid

open access: yesReproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose In mouse embryos derived from round spermatid injection (ROSI), low developmental potential due to abnormal histone modification is improved by histone deacetylase (HDAC) inhibitors. However, some studies suggest that the use of such inhibitors leads to the birth of hypomorphic offspring.
Seiji Watanabe   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy