Results 61 to 70 of about 27,921 (258)
Luteinizing hormone receptor knockout mouse: What has it taught us?
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
Cryptorchidism: Novel genetic insights into CCDC149 mutations
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du +8 more
wiley +1 more source
The fallopian tube (FT) is an important reproductive organ in females. The luminal epithelium of the FT is composed of highly polarized secretory and ciliated cells.
Maobi Zhu, Tomohiko Iwano, Sen Takeda
doaj +1 more source
Mouse genome engineering uncovers 18 genes dispensable for male reproduction
Abstract Background Male infertility is an intricate multifactorial disease involving the interplay between genetic and environmental factors. Genetic anomalies account for more than 15% of all male infertility cases; however, diagnosing them exhibits enormous challenges due to variable symptomatic presentations and limited knowledge of gene functions.
Hsin‐Yi Chang +7 more
wiley +1 more source
In order to observe the histopathological changes of the layer oviduct cysts infected with Gallibacterium anatis, target genes were amplified by PCR from genome DNA extracted from lung, trachea, oviduct and ovary of nine birds infected naturally, using ...
LIU Hui-min +4 more
doaj +1 more source
Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz +4 more
wiley +1 more source
On day 5 of incubation, 0.64mg of estradiol benzoate (EB) was administered to fertilized eggs to investigate its effects on the differentiation and development of the oviduct in female chickens.
Shinya Masuda, Fukashi Koyanagi
doaj +1 more source
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández +9 more
wiley +1 more source
The aim of this study was to determine whether ghrelin is produced in the oviduct of Japanese quail. Japanese quail laying hens and 20-days-old immature ones were used.
Yukinori Yoshimura +3 more
doaj +1 more source
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu +2 more
wiley +1 more source

