Results 61 to 70 of about 36,935 (226)

A Comparative Study of Porcine and Ovine Derived Defibrotide: Coagulation Profiles, Molecular Characteristics, and DNA Content

Clinical and Applied Thrombosis/Hemostasis
Background Defibrotide is a DNA-derived polyelectrolyte with anti-ischemic and antithrombotic effects, primarily used in post-bone marrow transplantation (BMT) veno-occlusive disease (VOD).
Hussein Abourahma BS, Prakasha Kempaiah PhD, Ambar Farooqui MD, Emily Krupa BS, Omer Iqbal MD, Jawed Fareed PhD, Yiming Yao MS   +6 more
doaj   +1 more source

Peroxisome proliferator-activated receptor gamma (PPARγ) agonist fails to overcome trans-10, cis-12 conjugated linoleic acid (CLA) inhibition of milk fat in dairy sheep

Animal, 2018
The trans-10, cis-12 conjugated linoleic acid (CLA) causes milk fat depression by downregulating expression of genes and transcription factors involved in lipogenesis and it has been proposed that peroxisome proliferator-activated receptor gamma (PPARγ ...
E.C. Sandri, M. Camêra, E.M. Sandri, K.J. Harvatine, D.E. De Oliveira   +4 more
doaj   +1 more source

Overview of the re‐evaluation of trace elements as nutritional feed additives in the European Union: characterization, safety, and efficacy

Journal of the Science of Food and Agriculture, EarlyView.
Abstract The re‐evaluation of feed additives in the European Union was outlined in the Regulation (EC) No 1831/2003. The primary objectives were to ensure safety and verify efficacy, as well as to update authorizations and phase out unsafe additives or those in which the industry expressed no interest.
Gloria López‐Gálvez, Maria de Lourdes Bastos, Francesco Cubadda, Mikolaj A Gralak, Christer Hogstrand, Matteo L Innocenti, Joop de Knecht, Marta López‐Alonso, Alberto Mantovani, Alena Pechová, Fernando Ramos, Jürgen Gropp   +11 more
wiley   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Effect of vitamin A supplementation at different gaseous environments on in vitro development of pre-implantation sheep embryos to the blastocyst stage

Animal, 2010
Vitamin A (all-trans retinol) is an important antioxidant whose role in embryo development in vitro and in vivo is well established. Oxidative stress is a major cause of defective embryo development.
N. Rajesh, M.B. Shankar, M. Deecaraman
doaj   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Generation and characterization of an ovine cell line derived from peripheral blood and its potential use in the study of livestock and zoonotic viral infections

Virology Journal
Background Mesenchymal stromal cells (MSCs) are a population of undifferentiated, non-hematopoietic fibroblast-like cells isolated from several tissues with multipotent differentiation capacity in vitro.
S. Moreno, C. Sanjurjo-Rodríguez, S. Rodríguez-Fernández, L. Jiménez-Cabello, E. Calvo-Pinilla, A. Nogales, A. Marín-López, J. Ortego, A. Brun, S. Díaz-Prado, G. Lorenzo   +10 more
doaj   +1 more source

Observed Trace Mineral Deficiencies in a Group of Locally Harvested Sheep in Hawai’i

Veterinary Sciences
Trace minerals (TM) play a critical role in the health and productivity of small ruminants. They are essential for various physiological functions, including growth, reproduction, and immune response, yet research on their status in Hawai’i is notably ...
Shaye N. R. Nishimura, Janae S. Bulosan, Mark S. Thorne, Melelani A. Oshiro, Jenee S. Odani, Caleb C. Reichhardt   +5 more
doaj   +1 more source

Benzimidazole Anthelmintic Compounds Albendazole and Fenbendazole Show Distinct Toxicity on the Nitrogen Fixing Bacterium Mesorhizobium loti and Its Symbiosis With Lotus japonicus

Environmental Toxicology, EarlyView.
ABSTRACT Veterinary medicines, which reach the soil mostly through the application of contaminated manures, can affect beneficial soil microorganisms, such as nitrogen‐fixing rhizobia bacteria, which engage in important symbiotic associations with plants.
Polyxeni Gorgia, Stathis Lagos, Christina N. Nikolaou, Nikoleta Basdeki, Christos Papadopoulos, Dimitrios G. Karpouzas, Daniela Tsikou   +6 more
wiley   +1 more source

Prediction of Subcutaneous Fat Thickness (SFT) in Pantaneiro Lambs: A Model Based on Adipometer and Body Measurements for Android Application

AgriEngineering
The increasing adoption of digital technologies in the agriculture sector has significantly contributed to optimizing on-farm routines, especially in data-driven decision-making. This study aimed to develop an application to determine the slaughter point
Adrielly Lais Alves da Silva, Marcus Vinicius Porto dos Santos, Marcelo Corrêa da Silva, Hélio Almeida Ricardo, Marcio Rodrigues de Souza, Núbia Michelle Vieira da Silva, Fernando Miranda de Vargas Junior   +6 more
doaj   +1 more source