Results 71 to 80 of about 31,846 (191)

Model Systems of Gammaherpesvirus Infection, Immunity, and Disease

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT Epstein‐Barr virus (EBV) and Kaposi's sarcoma‐associated herpesvirus (KSHV) are oncogenic human gammaherpesviruses (GHVs) associated with a broad spectrum of malignancies and chronic diseases. However, direct studies of these viruses in humans are limited by ethical constraints, technical challenges, and their strict species specificity.
Arundhati Gupta, Renfeng Li, Kathy Shair, Shou‐Jiang Gao   +3 more
wiley   +1 more source

Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.

EFSA Journal, Volume 17, Issue 2, February 2019., 2019
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on safety and efficacy of sodium molybdate dihydrate for sheep, based on a dossier submitted for the re‐evaluation of the additive.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Maryline Kouba, Mojca Kos Durjava, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Gerhard Flachowsky, Jürgen Gropp, Francesco Cubadda, Gloria López‐Gálvez, Alberto Mantovani   +22 more
wiley   +1 more source

Validation and functional analysis of Ovine Herpesvirus 2-encoded microRNAs [PDF]

, 2016
Ovine herpesvirus 2 (OvHV-2) is a gammaherpesvirus of domestic sheep and causes the lymphoproliferative disease malignant catarrhal fever (MCF) in susceptible ruminants, including cattle. Sheep are latently infected but do not develop disease.
Nightingale, Katie
core  

From humans to hydra: patterns of cancer across the tree of life

Biological Reviews, Volume 93, Issue 3, Page 1715-1734, August 2018., 2018
ABSTRACT Cancer is a disease of multicellularity; it originates when cells become dysregulated due to mutations and grow out of control, invading other tissues and provoking discomfort, disability, and eventually death. Human life expectancy has greatly increased in the last two centuries, and consequently so has the incidence of cancer.
Thales A. F. Albuquerque, Luisa Drummond do Val, Aoife Doherty, João Pedro de Magalhães   +3 more
wiley   +1 more source

Malignant catarrhal fever of cattle is associated with low abundance of IL-2 transcript and a predominantly latent profile of ovine herpesvirus 2 gene expression. [PDF]

PLoS ONE, 2009
BACKGROUND:Malignant catarrhal fever (MCF) is a lethal disease of cattle, characterized by vasculitis, necrosis, and accumulation of activated, dysregulated cytotoxic lymphocytes in various tissues. Ovine gamma herpesvirus 2 (OvHV-2) is a causative agent
Claudia S Meier-Trummer, Hubert Rehrauer, Marco Franchini, Andrea Patrignani, Ulrich Wagner, Mathias Ackermann   +5 more
doaj   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

International Journal of Cancer, Volume 157, Issue 2, Page 371-383, 15 July 2025.
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita, Chiara Maria Mazzanti, Francesca Lessi, Caterina Marchiò, Cristian Scatena, Michele Menicagli, Matteo Ghilli, Manuela Roncella, Antonio Giuseppe Naccarato, Anna Sapino, Jacob Hochman, Mauro Pistello, Generoso Bevilacqua   +12 more
wiley   +1 more source

Novel virus-encoded microRNA molecules expressed by ovine herpesvirus 2-immortalized bovine T-cells

, 2012
A number of herpesviruses have now been shown to encode microRNAs (miRNAs) that have roles in control of both viral and cellular gene expression. Ovine herpesvirus 2 (OvHV-2) is the causative agent of sheep-associated malignant catarrhal fever, a fatal ...
George C. Russell, Claire S. Levy, Robert G. Dalziel, John Hopkins   +3 more
core   +1 more source

Advancing ORFV‐Based Therapeutics to the Clinical Stage

Reviews in Medical Virology, Volume 35, Issue 3, May 2025.
ABSTRACT The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses without inducing significant anti‐vector immunity.
Matthias Helmold, Ralf Amann
wiley   +1 more source

In Situ Hybridization for Localization of Ovine Herpesvirus 2, the Agent of Sheep-Associated Malignant Catarrhal Fever, in Formalin-Fixed Tissues

Veterinary Pathology-Supplement, 2018
A constraint on understanding the pathogenesis of malignant catarrhal fever (MCF) is the limited number of tools to localize infected cells. The amount of detectable virus, visualized in the past either by immunohistochemistry or in situ hybridization ...
P. Pesavento, C. Cunha, Hong Li, Kenneth A. Jackson, D. O'Toole   +4 more
semanticscholar   +1 more source

First Study of Molecular detection of Ovine Herpesvirus 2 DNA using heminested PCR in Pakistan

, 2020
The authors have requested that this preprint be withdrawn due to erroneous posting.
Aayesha Riaz, Inga Dry, R. Dalziel, S. Rehman, M. Shah, N. Akhtar, A. Yousaf, R. Baig   +7 more
semanticscholar   +1 more source