46,XY ovotesticular disorders of sex development: A therapeutic challenge [PDF]
Pediatric Reports, 2017 46,XY ovotesticular disorder of sex development is extremely rare and indicates the presence of both testis and ovary in the same patient. Gender assignment in newborns represents a therapeutic challenge.
Maria-Grazia Scarpa +2 more
doaj +6 more sources
Ovotesticular disorders of sex development with dysgerminoma in a 46, XX/46, XY female: A case report [PDF]
Gynecologic Oncology ReportsThe diagnosis of ovotesticular disorders of sex development can only be confirmed when both testicular and ovarian tissues are present simultaneously in the same individual, regardless of the patient’s karyotype. This report aims to discuss the diagnosis
Yafei Xue +4 more
doaj +4 more sources
Management of Differences in Sexual Development: Evolution of an Approach for a Resource-Limited Setting [PDF]
The Annals of African Surgery, 2022 Background: The approach to management of patients with disorders of sex development (DSD) has been refined over the past two decades. We sought to review DSD cases at our hospital and hypothesized that age at presentation would decline over time ...
Erik Hansen +3 more
doaj +3 more sources
Diagnosis and surgical decision-making of a 46, XX ovotesticular disorders of sex development patient: a case report [PDF]
Frontiers in SurgeryBackgroundOvotesticular disorder of sex development is a rare form of disorder of sex development that manifests as ovotestis in individuals. The precise diagnosis and the choice of surgical procedures are still in conflict condition due to the rarity of
Hanxing Zhao +7 more
doaj +2 more sources
Ultrasonography for disorders of sex development in pediatrics [PDF]
Frontiers in PediatricsObjectiveThis study aimed to evaluate the clinical value of ultrasonography in the management of disorders of sex development (DSDs).MethodsUltrasonographic appearance and clinical data of 82 cases with DSD were reviewed retrospectively.ResultsIn total ...
Yuting Wu +3 more
doaj +2 more sources
Gender Dysphoria in a Patient With Ovotesticular Disorder of Sex Development. [PDF]
JCEM Case Rep, 2023 Abstract Ovotesticular disorder of sex development (OT-DSD) is a rare condition characterized by the presence of both ovarian and testicular tissue in the gonads. Management and sex designation of these patients depend on several factors, and an underlying potential for gender dysphoria should be acknowledged.
Moreno T, Ribeiro S, Rodrigues P.
europepmc +3 more sources
A parthenogenetic maternal and double paternal contribution to an ovotesticular disorder of sex development [PDF]
Molecular Cytogenetics, 2014 BACKGROUND: An ovotesticular disorder of sex development (OT-DSD) was rarely found in human. The mechanism causing such condition is poorly understood. We hereby reported a 11-year-old child with OT-DSD and a karyotype 46,XX/46,XY, a single maternal and ...
Cui Zhang +9 more
core +4 more sources
Ovotesticular disorder of sex development in a 46 XY adolescent: a rare case report with review of the literature [PDF]
BMC Women's Health, 2023 Introduction : Ovotestis is a rare cause of sexual ambiguity characterized by the presence in a patient of both testicular and ovarian tissue, leading to the development of both male and female structures.
Koui Bbs +6 more
doaj +2 more sources
Etiology and Clinical Presentation of Disorders of Sex Development in Kenyan Children and Adolescents [PDF]
International Journal of Endocrinology, 2019 Objective. The purpose of this study was to describe baseline data on etiological, clinical, laboratory, and management strategies in Kenyan children and adolescents with Disorders of Sex Development (DSD). Methods.
Prisca Amolo +3 more
doaj +4 more sources
NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development. [PDF]
Genet Med, 2017 We aimed to identify the genetic cause in a cohort of 11 unrelated cases and two sisters with 46,XX SRY-negative (ovo)testicular disorders of sex development (DSD).Whole-exome sequencing (n = 9), targeted resequencing (n = 4), and haplotyping were performed. Immunohistochemistry of sex-specific markers was performed on patients' gonads.
Baetens D +9 more
europepmc +5 more sources