46,XY ovotesticular disorders of sex development: A therapeutic challenge [PDF]
Pediatric Reports, 2017 46,XY ovotesticular disorder of sex development is extremely rare and indicates the presence of both testis and ovary in the same patient. Gender assignment in newborns represents a therapeutic challenge.
Maria-Grazia Scarpa +2 more
doaj +8 more sources
Ovotesticular disorders of sex development with dysgerminoma in a 46, XX/46, XY female: A case report [PDF]
Gynecologic Oncology ReportsThe diagnosis of ovotesticular disorders of sex development can only be confirmed when both testicular and ovarian tissues are present simultaneously in the same individual, regardless of the patient’s karyotype. This report aims to discuss the diagnosis
Yafei Xue +4 more
doaj +6 more sources
Diagnosis and surgical decision-making of a 46, XX ovotesticular disorders of sex development patient: a case report [PDF]
Frontiers in SurgeryBackgroundOvotesticular disorder of sex development is a rare form of disorder of sex development that manifests as ovotestis in individuals. The precise diagnosis and the choice of surgical procedures are still in conflict condition due to the rarity of
Hanxing Zhao +7 more
doaj +4 more sources
NR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex development [PDF]
Genetics in Medicine, 2017 We aimed to identify the genetic cause in a cohort of 11 unrelated cases and two sisters with 46,XX SRY-negative (ovo)testicular disorders of sex development (DSD).Whole-exome sequencing (n = 9), targeted resequencing (n = 4), and haplotyping were performed. Immunohistochemistry of sex-specific markers was performed on patients' gonads.
Frank Peelman +2 more
exaly +6 more sources
Ultrasonography for disorders of sex development in pediatrics [PDF]
Frontiers in PediatricsObjectiveThis study aimed to evaluate the clinical value of ultrasonography in the management of disorders of sex development (DSDs).MethodsUltrasonographic appearance and clinical data of 82 cases with DSD were reviewed retrospectively.ResultsIn total ...
Yuting Wu +3 more
doaj +2 more sources
Urology Case Reports, 2016 Ovotesticular disorder of sex development is historically thought to confer a relatively low risk of germ cell malignancy relative to other disorders of sex development.
Russell E.N. Becker, Ardavan Akhavan
doaj +3 more sources
BMC Women's Health, 2023 Introduction : Ovotestis is a rare cause of sexual ambiguity characterized by the presence in a patient of both testicular and ovarian tissue, leading to the development of both male and female structures.
Koui Bbs +6 more
doaj +3 more sources
Retrospective analysis of children with 46,XX testicular/ovotesticular DSD: a 10-year single-center experience [PDF]
Frontiers in EndocrinologyPurpose46,XX testicular/ovotesticular differences/disorders of sexual development (TDSD/OTDSD) are rare in childhood and exhibit marked distinctions compared to those in adulthood.
Yan Gong +10 more
doaj +2 more sources
Ovarian malignancy in an individual with 46,XY ovotesticular disorder of sexual development – A case report [PDF]
Urology Case ReportsDisorders of sexual development (DSD) are diseases resulting from aberrations in sex chromosomes, gonadal, and internal/external genitalia development resulting in various phenotypes.
James I. Griggers +2 more
doaj +2 more sources
Ovotesticular Disorders of Sex Development: Improvement in Spermatogonia after Removal of Ovary and Müllerian Structures [PDF]
Journal of Pediatric and Adolescent Gynecology, 2019 Ovotesticular disorders of sex development is a condition defined as the presence of ovarian tissue containing ovarian follicles and testicular tissue containing seminiferous tubules in the same individual.We report on a 19-year-old who is phenotypically male, with a 46,XX/46,XY mosaicism karyotype, who presented later in life with cyclical abdominal ...
Ana Vetriana, Abd Wahab +2 more
exaly +3 more sources