True hermaphrodite presenting as primary amenorrhea
Indian Journal of Endocrinology and Metabolism, 2012 True hermaphrodite is one of the rare variety of disorders of sex development. Most of them are genotypically females (46 XX) and present as under virilized males. Features of hyperandrogenism are present in those reared as females.
Lal Bahadur Palo +3 more
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46 XX Ovotesticular Disorder of Sex Development with Gonadotropin-Releasing Hormone Receptor, Autosomal Recessive Heterozygous Missense Mutation and Autosomal Dominant Heterozygous Missense Mutation of the PROKR2 Gene: A Case Report [PDF]
Global Medical GeneticsTrue hermaphroditism is a disorder of sex development (DSD), accounting for less than 5% of all DSD cases, defined by the simultaneous presence of testicular tissue and ovarian tissue in the same individual.
Francesca Peranzoni +3 more
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46,XX Differences of Sex Development outside congenital adrenal hyperplasia: pathogenesis, clinical aspects, puberty, sex hormone replacement therapy and fertility outcomes [PDF]
Frontiers in EndocrinologyThe term ‘differences of sex development’ (DSD) refers to a group of congenital conditions that are associated with atypical development of chromosomal, gonadal, and/or anatomical sex.
Marianna Rita Stancampiano +3 more
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Specificity of Key Sex Determination Genes in a Mammal with Ovotestes: The European Mole Talpa europaea [PDF]
AnimalsHere, for the first time, the structure of genes involved in sex determination in mammals (full Sry and partial Rspo1, Eif2s3x, and Eif2s3y) was analyzed for the European mole Talpa europaea with ovotestes in females.
Alexey Bogdanov +2 more
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TIP Revista Especializada en Ciencias Químico-Biológicas, 2011 Durante el estudio de la biología reproductiva de Anchoa mitchilli en la laguna de Pueblo Viejo, Veracruz, se analizaron 3,385 individuos (1,530 machos y 1,855 hembras).
Manuel Castillo-Rivera +2 more
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Yolk proteins of the schistosomiasis vector snail Biomphalaria glabrata revealed by multi-omics analysis [PDF]
Scientific ReportsVitellogenesis is the most important process in animal reproduction, in which yolk proteins play a vital role. Among multiple yolk protein precursors, vitellogenin (Vtg) is a well-known major yolk protein (MYP) in most oviparous animals.
Mohamed R. Habib +5 more
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Is it possible to separate the testicular and ovarian components of an ovotestis?
Journal of Pediatric UrologyThe presence of an ovotestis is a rare etiology of differences of sex development. Histologically, ovotestis come in two forms: 1) Mixed or 2) Bipolar.We hypothesize that it is surgically impossible to cleanly separate and preserve either the testicular or ovarian component of an ovotestis.Twenty human gonads with a previous diagnosis of ovotestis were
Laurence Baskin +2 more
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Cellular fate of intersex differentiation
Cell Death and Disease, 2021 Infertile ovotestis (mixture of ovary and testis) often occurs in intersex individuals under certain pathological and physiological conditions. However, how ovotestis is formed remains largely unknown.
Xin Wang +6 more
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Germ cell and other tumors in individuals with differences in sex development. [PDF]
CA Cancer J ClinAbstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Witchel SF, Reyes-Múgica M.
europepmc +2 more sources
Frontiers in Genetics, 2022 Unlike gonochoristic fishes, sex is fixed after gonadal differentiation (primary sex determination), and sex can be altered in adults (secondary sex determination) of hermaphroditic fish species. The secondary sex determination of hermaphroditic fish has
Peng-Wei Tseng +7 more
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