Results 121 to 130 of about 146,853 (289)

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

open access: yesAndrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret   +5 more
wiley   +1 more source

Effects of Exogenous Supplementation of Progesterone on Conception Rates in Lactating Murrah Buffaloes

open access: yesVeterinary Sciences
The objective of this study was to deduce the effect of exogenous supplementation of progesterone as an intramuscular injection at the time of artificial insemination (AI) on time of ovulation and conception rate in lactating Murrah buffaloes. A total of
Rajesh Kumar   +4 more
doaj   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

open access: yesAndrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

What Moves Men to Change? A Mixed‐Methods Study on Facilitators and Barriers of Lifestyle Changes in Men Seeking Fertility Care

open access: yesAndrology, EarlyView.
ABSTRACT Background An unhealthy lifestyle negatively affects male fertility. Despite this, men that are part of an infertile couple often fail to improve their lifestyle and evidence on influencing factors is limited. Objectives To identify facilitators and barriers involved in lifestyle changes of men seeking fertility care and in lifestyle ...
Wiep R. de Ligny   +5 more
wiley   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

open access: yesAndrology, EarlyView.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang   +4 more
wiley   +1 more source

Progestational Steroids: Some Moral Problems [PDF]

open access: yes, 1958
EDITOR\u27S NOTE. Physicians now have at their disposal certain new drugs which apparently are proving effective in the correction of various gynecological disorders. But because these drugs can also inhibit ovulation and consequently produce
Lynch, John J.
core   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

open access: yesAndrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda   +7 more
wiley   +1 more source

Is it safe to preserve uterus after live birth following progestin‐based fertility‐sparing treatment for endometrial cancer or atypical hyperplasia: A long‐term retrospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Achieving live birth following fertility‐sparing treatment is associated with improved recurrence‐free survival among patients with endometrial cancer/atypical endometrial hyperplasia. Abstract Introduction We aimed to assess the safety of continuous uterus‐preserving treatment among patients with endometrial cancer (EC) and atypical endometrial ...
Yiqin Wang   +9 more
wiley   +1 more source

Discrepancy in menstrual and ultrasound‐based gestational age is associated with chromosomal aberrations and adverse pregnancy outcomes—Results from a nationwide cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
A smaller than expected crown–rump length (CRL) relative to last menstrual period was strongly associated with increased risk of chromosomal abnormalities, adverse pregnancy outcomes, and obstetric complications. Conversely, a larger than expected CRL was associated with a reduced risk of these outcomes.
Simone Hansen   +9 more
wiley   +1 more source

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