Results 201 to 210 of about 146,853 (289)

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai   +15 more
wiley   +1 more source

Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo   +4 more
wiley   +1 more source

Clinal Variation in Reproductive Modes and Offspring Body Condition Across a Contact Zone of a Bimodal Viviparous Salamander

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
We examined clinal gradients in reproductive modes and associated offspring body condition across a hybrid zone between two bimodal viviparous subspecies of Salamandra salamandra. We found a clear cline in reproductive modes, with pure modes at the extremes and mixed modes in central populations.
Clara Figueiredo‐Vázquez   +2 more
wiley   +1 more source

Letters [PDF]

open access: yes, 1969
Catholic Physicians\u27 Guild
core   +1 more source

Effect of Probiotic Supplementation on Reproductive Outcomes of Women With Polycystic Ovary Syndrome Who Are Candidates for Intrauterine Insemination: A Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Probiotic supplementation for 8 weeks in women with PCOS who were candidates for IUI was associated with higher endometrial thickness, indicating a potential role in improving endometrial receptivity. ABSTRACT Introduction Evidence showed that microbial dysbiosis may lead to poor fertility outcomes. Today, therapy with probiotics, especially when using
Tahereh Behroozilak   +2 more
wiley   +1 more source

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