Results 281 to 290 of about 136,516 (311)

Maternal Calcium Intake at 36 Weeks' Gestation and Pre‐Eclampsia Risk—A Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 6, Page 816-825, May 2025.
ABSTRACT Objective The objective of this study is to examine the association between dietary calcium intake (Ca) and pre‐eclampsia (PE). Design Cohort study. Setting Inner‐city hospital. Population A total of 2838 women with singleton pregnancies at 35+0–36+6 weeks' gestation, including 96 (3.4%) who subsequently developed PE.
Anastasija Arechvo   +7 more
wiley   +1 more source

Human efferent ductules and epididymis display unique cell lineages with motile and primary cilia

open access: yesAndrology, Volume 13, Issue 4, Page 894-910, May 2025.
Abstract Background Previous research has illustrated the role of cilia as mechanical and sensory antennae in various organs within the mammalian male reproductive system across different developmental stages. Despite their significance in both organ development and homeostasis, primary cilia in the human male reproductive excurrent duct have been ...
Ludovic Vinay   +2 more
wiley   +1 more source

Elevated Linoleic Acid Intake Becomes a Risk Factor for Polycystic Ovary Syndrome by Affecting Ovarian Granulosa Cells

open access: yesThe FASEB Journal, Volume 39, Issue 7, 15 April 2025.
This study explored the relationship between dietary LA intake and PCOS. Animal experiments demonstrated that increased intake of LA led to PCOS‐like changes in mice, presenting with disordered estrous cycles, polycystic ovaries, and hyperandrogenism.
Wenying Zhang, Fuju Wu
wiley   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Multiomics and Systematic Analyses Reveal the Roles of Hemoglobin and the HIF‐1 Pathway in Polycystic Ovary Syndrome

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
High‐end normal hemoglobin levels are associated with an increased odds of polycystic ovary syndrome (PCOS), potentially through a mechanism of elevating testosterone levels involving the hypoxia‐inducible factor 1 (HIF‐1) pathway. These findings provide novel insights into the pathophysiology of PCOS and highlight that hemoglobin levels may serve as a
Guiquan Wang   +13 more
wiley   +1 more source

A review of recommendations, efficacy, and patient safety for over-the-counter norgestrel for daily contraception. [PDF]

open access: yesExplor Res Clin Soc Pharm
Tran G   +5 more
europepmc   +1 more source

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