Results 71 to 80 of about 1,199,788 (389)

Pharmacokinetic, pharmacodynamic, and clinical aspects of ovulation induction agents: A review of the literature

Journal of the Turkish-German Gynecological Association, 2017
Controlled ovarian hyperstimulation is a key step for successful outcomes of assisted reproductive technique cycle outcomes. Many medications are available, which are commonly useed solely or in combination to achieve multiple follicular development ...
S. Kahyaoğlu, B. Yilmaz, A. Işık
semanticscholar   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

Successful induction of ovulation and completed pregnancy using recombinant human luteinizing hormone and follicle stimulating hormone in a woman with Kallmann's syndrome [PDF]

, 2017
The induction of ovulation in women with hypogonado-trophic hypogonadism requires follicle stimulating hormone (FSH) for follicular growth and both FSH and luteinizing hormone (LH) to induce optimal follicular steroidogenesis.
Franks, S., Kousta, E., Loumaye, E., Piazzi, A., White, D.M.   +4 more
core  

Circadian regulation of reproduction: From gamete to offspring [PDF]

, 2013
P01326625; Grants: GNT0519315Few challenges are more critical to the survival of a species than reproduction. To ensure reproductive success, myriad aspects of physiology and behaviour need to be tightly orchestrated within the animal, as well as timed ...
Boden, M., Kennaway, D., Varcoe, T.
core   +1 more source

Baseline AMH Level Associated With Ovulation Following Ovulation Induction in Women With Polycystic Ovary Syndrome.

Journal of Clinical Endocrinology and Metabolism, 2016
CONTEXT Anti-Müllerian hormone (AMH) reduces aromatase activity and sensitivity of follicles to FSH stimulation. Therefore, elevated serum AMH may indicate a higher threshold for response to ovulation induction in women with polycystic ovary syndrome ...
S. Mumford, R. Legro, M. Diamond, C. Coutifaris, A. Steiner, W. Schlaff, R. Alvero, G. Christman, P. Casson, Hao Huang, N. Santoro, E. Eisenberg, Heping Zhang, M. Cedars   +13 more
semanticscholar   +1 more source

PABPN1 Couples the Polyadenylation and Translation of Maternal Transcripts to Mouse Oocyte Meiotic Maturation

Advanced Science, EarlyView.
This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai, Yu‐Ke Wu, Shuai‐Bo Pi, Feng‐Jie Hu, Yun‐Wen Wu, Hang Qi, Zhiyi Li, Zhi‐Yan Jiang, Long‐Wen Zhao, Heng‐Yu Fan   +9 more
wiley   +1 more source

The loss of imprinted DNA methylation in mouse blastocysts is inflicted to a similar extent by in vitro follicle culture and ovulation induction.

Molecular human reproduction, 2016
STUDY HYPOTHESIS Does in vitro follicle culture (IFC) have an effect on maintenance of imprinted DNA methylation in preimplantation mouse embryos? STUDY FINDING We report similar alterations in the methylation pattern of H19 imprinted maternally ...
M. D. Saenz-de-Juano, K. Billooye, J. Smitz, E. Anckaert   +3 more
semanticscholar   +1 more source

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

Advanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
wiley   +1 more source

Mechanical shock during egg de-adhesion and post-ovulatory ageing contribute to spontaneous autopolyploidy in white sturgeon culture (Acipenser transmontanus) [PDF]

, 2020
Spontaneous autopolyploidy, a 1.5x increase in genome size resulting from second polar body retention after fertilization, has been documented in cultured sturgeons, with the proportion of spontaneous autopolyploid progeny ranging widely among maternal ...
Conte, FS, Cooley-Rieders, C, Fiske, AJ, Leal, MJ, Schreier, AD, Todgham, AE, Van Eenennaam, JP   +6 more
core  

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science, EarlyView.
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
wiley   +1 more source