Results 101 to 110 of about 66,023 (384)

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

open access: yesCancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao   +12 more
wiley   +1 more source

Flora da Paraíba, Brasil: Solanum L. (Solanaceae) Flora of Paraíba, Brazil: Solanum L. (Solanaceae)

open access: yesActa Botânica Brasílica, 2009
Neste trabalho apresenta-se o tratamento taxonômico do gênero Solanum, como parte do projeto "Flora da Paraíba", que vem sendo realizado com o objetivo de identificar e catalogar as espécies da flora local.
Maria de Fátima Agra   +2 more
doaj   +1 more source

Distribution and reproduction of the Arctic ctenophore Mertensia ovum in the Baltic Sea

open access: yes, 2013
Species identification based on morphological characteristics has caused misidentifications and led to twisted views of abundances and roles of ctenophores.
M. Lehtiniemi   +14 more
semanticscholar   +1 more source

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

open access: yesChemistry – A European Journal, EarlyView.
The synthesis of multicomponent cancer vaccines on AuNP carriers could be rationalized by the simultaneous functionalization of the antigen and immunomodulator components on the same particles. Immunization with a “diluted” amount of MUC1‐functionalized AuNPs is still capable of eliciting a strong immune response.
Mattia Ghirardello   +8 more
wiley   +1 more source

Pre‐oviposition development of the brown anole (Anolis sagrei)

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling   +9 more
wiley   +1 more source

In Vitro Fertilization: Trends, Criticism and Challenges

open access: yesRGUHS Journal of Nursing Sciences
Assisted Reproductive Technology ART frequently uses in vitro fertilization IVF a sophisticated method of treating infertility in which a donor or non-donor ovum is fertilized in a laboratory using either donor sperm or spouses semen.
Ige Busayo Sarah   +2 more
doaj   +1 more source

A Case of Miscarriage Caused by a Small Uterus following Childhood Chemotherapy

open access: yesCase Reports in Oncology, 2019
A majority of miscarriages have been thought to be caused by fertile ovum abnormalities; however, our findings suggest that a small uterus can also potentially cause miscarriage.
Rie Kitayama
doaj   +1 more source

The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells

open access: yesExploration, EarlyView.
Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen   +29 more
wiley   +1 more source

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