Results 151 to 160 of about 56,247 (306)

Miscarriage treatment-related adverse events: A nationwide registry study from Finland. [PDF]

open access: yesActa Obstet Gynecol Scand
Helle N   +5 more
europepmc   +1 more source

Acetylome Analyses Provide New Insights Into the Effects of Childhood Allergic Rhinitis on Olfactory Bulb‐Dependent Olfactory Impairment

open access: yes
Allergy, EarlyView.
Ruikun Wang   +10 more
wiley   +1 more source

Autophagy Inhibition by Fangji Huangqi Decoction Enhances Tumor Immunogenicity and Potentiates PD‐1 Blockade

open access: yesCancer Science, EarlyView.
In tumor cells, MHC‐I is typically degraded through autophagy, leading to reduced antigen presentation. However, Fangji Huangqi Decoction (FJHQ), acting as an autophagy inhibitor, suppresses lysosomal acidification, which in turn inhibits the degradation of MHC‐I. This results in increased surface expression of MHC‐I on tumor cells.
Yuxiao Jiang   +18 more
wiley   +1 more source

IL‐1β and IL‐6 synergistically drive murine TFH cell differentiation and maintenance in vitro

open access: yesImmunology &Cell Biology, EarlyView.
We define a physiologically relevant in vitro system that demonstrates the combined function of T‐cell receptor signaling, IL‐6 and IL‐1β individually and jointly to promote TFH cell differentiation. These findings identify the essential requirements for generating functional TFH cells and clarify how cytokines shape their differentiation within the ...
Juliana Restrepo Munera, S Rameeza Allie
wiley   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

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