Results 171 to 180 of about 27,515 (301)

Indole‐3‐Propionic Acid Drives Dendritic H3K27 Acetylation to Enhance CD8+ T Cell Immunity in Hepatocellular Carcinoma

open access: yesCancer Science, EarlyView.
The gut microbiota metabolite indole ‐ 3 ‐ propionic acid(IPA) enhanced the inhibitory effect of SCB on tumor growth in HCC mice. IPA upregulated IL‐12A expression through facilitating acetylation of H3K27 in DCs. IPA elevated IL‐12A expression in DCs to promote CD8+ T cell anti‐tumor immunity and ultimately enhances the efficacy of SCB therapy against
Rui Zhao   +7 more
wiley   +1 more source

The Role of IGF2BP3‐Mediated Immune Response Activation in Enhancing Immunotherapy of Koumine for Gastric Cancer

open access: yesCancer Science, EarlyView.
Koumine binds IGF2BP3 and promotes its proteasomal degradation, reducing m6A on EED mRNA, accelerating EED decay, lowering H3K27me3, and promoting IRF transcription, thereby restoring MHC‐I and enhancing CD8+ T cell killing. ABSTRACT Resistance to immune checkpoint blockade in gastric cancer often arises from defective antigen presentation due to MHC‐I
Qiu Hongqiang   +10 more
wiley   +1 more source

Testicular Schistosomiasis Mimicking Testicular Tumour: A Case Report. [PDF]

open access: yesNiger Med J
Kabuga AI   +5 more
europepmc   +1 more source

Local Delivery of a Bio‐Engineered IL‐37 Fc‐Fusion Ameliorates Experimental Allergic Asthma in Mice

open access: yes
Allergy, EarlyView.
Lars P. Lunding   +3 more
wiley   +1 more source

Effects of the timing of testicular sperm retrieval on intracytoplasmic sperm injection outcomes. [PDF]

open access: yesClin Exp Reprod Med
Hwang TH   +8 more
europepmc   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

open access: yesClinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole   +4 more
wiley   +1 more source

Human Fertilised Ovum

open access: yes, 1983
Hewson, G. Everard
core  

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